AC T02462
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ID T02462
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DT 02.06.1998 (created); oke.
DT 02.06.2016 (updated); mom.
CO Copyright (C), QIAGEN.
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FA NFATc4
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SY NF-AT3; NF-ATc4; NFAT3; NFATC4; Nuclear Factor of Activated T-cells 3.
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G004701 NFATC4; HGNC: NFATC4.
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CL C0052; REL/NFAT; 6.1.3.0.4.
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SF Rel-homology domain is important for interactions with C/EBPalpha [3];
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CP ZR75-1, MDA-MB-231, MDA-MB-435, MDA-MB-453 [4].
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FF activator [2] [3] [1];
FF acts synergistically and physically interacts with AP-1 factors [1];
FF functionally cooperates and physically interacts with C/EBP [3];
FF important regulator of immune-specific genes in response to intracellular Ca2+ [2] [1];
FF regulates adipocyte-specific genes [3];
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IN T00105 C/EBPalpha; human, Homo sapiens.
IN T00459 C/EBPbeta-FL; rat, Rattus norvegicus.
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MX M01734 V$NFAT3_Q3.
MX M07301 V$NFAT3_Q3_01.
MX M07608 V$NFAT_Q3.
MX M00935 V$NFAT_Q4_01.
MX M00302 V$NFAT_Q6.
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BS R29890.
BS R65453.
BS R29840.
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DR TRANSPATH: MO000026443.
DR TRANSCOMPEL: C00413.
DR UniProtKB: Q14934;
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RN [1]; RE0006880.
RX PUBMED: 9143705.
RA Rao A., Luo C., Hogan P.G.
RT Transcription factors of the NFAT family: regulation and function.
RL Annu. Rev. Immunol. 15:707-747 (1997).
RN [2]; RE0017299.
RX PUBMED: 7749981.
RA Hoey T., Sun Y. L., Williamson K., Xu X.
RT Isolation of two new members of the NF-AT gene family and functional characterization of the NF-AT proteins
RL Immunity 2:461-472 (1995).
RN [3]; RE0023877.
RX PUBMED: 12606546.
RA Yang T. T., Chow C. W.
RT Transcription cooperation by NFAT.C/EBP composite enhancer complex.
RL J. Biol. Chem. 278:15874-15885 (2003).
RN [4]; RE0053978.
RX PUBMED: 16219765.
RA Zhang H., Xie X., Zhu X., Zhu J., Hao C., Lu Q., Ding L., Liu Y., Zhou L., Liu Y., Huang C., Wen C., Ye Q.
RT Stimulatory cross-talk between NFAT3 and estrogen receptor in breast cancer cells.
RL J. Biol. Chem. 280:43188-43197 (2005).
RN [5]; RE0070940.
RX PUBMED: 21148296.
RA Wang Q., Zhou Y., Jackson L. N., Johnson S. M., Chow C. W., Evers B. M.
RT Nuclear factor of activated T cells (NFAT) signaling regulates PTEN expression and intestinal cell differentiation.
RL Mol. Biol. Cell 22:412-420 (2011).
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