AC T02516
XX
ID T02516
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DT 11.08.1998 (created); tme.
DT 11.02.2015 (updated); spk.
CO Copyright (C), QIAGEN.
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FA foxm1-isoform2
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SY HFH-11B.
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G004005 FOXM1; HGNC: FOXM1.
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CL C0023; fork head; 3.3.1.13.1.2.
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SZ 748 AA; 82.7 kDa (cDNA) (calc.), ca. 83 kDa (SDS)
XX
SQ MKTSPRRPLILKRRRLPLPVQNAPSETSEEEPKRSPAQQESNQAEASKEVAESNSCKFPA
SQ GIKIINHPTMPNTQVVAIPNNANIHSIITALTAKGKESGSSGPNKFILISCGGAPTQPPG
SQ LRPQTQTSYDAKRTEVTLETLGPKPAARDVNLPRPPGALCEQKRETCADGEAAGCTINNS
SQ LSNIQWLRKMSSDGLGSRSIKQEMEEKENCHLEQRQVKVEEPSRPSASWQNSVSERPPYS
SQ YMAMIQFAINSTERKRMTLKDIYTWIEDHFPYFKHIAKPGWKNSIRHNLSLHDMFVRETS
SQ ANGKVSFWTIHPSANRYLTLDQVFKQQKRPNPELRRNMTIKTELPLGARRKMKPLLPRVS
SQ SYLVPIQFPVNQSLVLQPSVKVPLPLAASLMSSELARHSKRVRIAPKVLLAEEGIAPLSS
SQ AGPGKEEKLLFGEGFSPLLPVQTIKEEEIQPGEEMPHLARPIKVESPPLEEWPSPAPSFK
SQ EESSHSWEDSSQSPTPRPKKSYSGLRSPTRCVSEMLVIQHRERRERSRSRRKQHLLPPCV
SQ DEPELLFSEGPSTSRWAAELPFPADSSDPASQLSYSQEVGGPFKTPIKETLPISSTPSKS
SQ VLPRTPESWRLTPPAKVGGLDFSPVQTSQGASDPLPDPLGLMDLSTTPLQSAPPLESPQR
SQ LLSSEPLDLISVPFGNSSPSDIDVPKPGSPEPQVSGLAANRSLTEGLVLDTMNDSLSKIL
SQ LDISFPGLDEDPLGPDNINWSQFIPELQ
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SC TREMBL #Q08050
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FT 234 321 
SM00339; forkneu4.
FT 235 325 
fork head domain [1].
FT 236 329 
PF00250; Fork head domain.
FT 236 329 
PS50039; FORK_HEAD_3.
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SF splice form of the HFH-11 gene, that lacks 2 exons;
SF the gene consists of 10+ exons (very unusual for fork head genes) [3];
SF the gene is located on chromosome 12p13 [2];
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CP studied only in mouse so far, see T02515.
CN studied only in mouse so far, see T02515.
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FF acts as transcriptional activator on an artificial promoter;
FF the alternatively spliced protein T02517 does not [3];
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IN T04096 Smad3-isoform1; human, Homo sapiens.
IN T04210 Smad3; mouse, Mus musculus.
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MX M00630 V$FOXM1_01.
MX M07255 V$FOXM1_Q6.
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BS R72809.
BS R05102.
BS R05101.
BS R05103.
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DR TRANSPATH: MO000026496.
DR EMBL: U74613;
DR UniProtKB: Q08050-2;
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RN [1]; RE0006655.
RA TRANSFAC_Team.
RT Revisions of transcription factor domains
RL TRANSFAC Reports 1:0002 (1998).
RN [2]; RE0006962.
RX PUBMED: 9441747.
RA Korver W., Roose J., Heinen K., Weghuis D. O., de Bruijn D., van Kessel A. G., Clevers H.
RT The human TRIDENT/HFH-11/FKHL12 gene: structure, localization and promoter characterization
RL Genomics 46:435-442 (1997).
RN [3]; RE0006963.
RX PUBMED: 9032290.
RA Ye H., Kelly T. F., Samadani U., Lim L., Rubio S., Overdier D. G., Roebuck K. A., Costa R. H.
RT Hepatocyte Nuclear Factor 3/ fork head homolog 11 is expressed in proliferating epithelial and mesenchymal cells of embryonic and adult tissues
RL Mol. Cell. Biol. 17:1626-1641 (1997).
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//