AC T02686
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ID T02686
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DT 16.04.1999 (created); vma.
DT 03.09.2015 (updated); jmh.
CO Copyright (C), QIAGEN.
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FA GATA-6
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SY GATA binding protein 6; GATA6.
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OS mouse, Mus musculus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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GE G004483 Gata6.
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CL C0004; CC; 2.2.1.1.6.
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CP E9.5 cells [3].
EX aorta,vascular smooth muscle cell,,fetal; detectable; RNA-in situ hybridization (not further specified); RNA (undefined); [2].
EX aortic valve,,,fetal; detectable; RNA-in situ hybridization (not further specified); RNA (undefined); [2].
EX cardiac muscle,,,fetal; detectable; RNA-in situ hybridization (not further specified); RNA (undefined); [2].
EX carotid artery,vascular smooth muscle cell,,fetal; detectable; RNA-in situ hybridization (not further specified); RNA (undefined); [2].
EX endocardium,,,fetal; detectable; RNA-in situ hybridization (not further specified); RNA (undefined); [2].
EX pulmonary artery,vascular smooth muscle cell,,fetal; detectable; RNA-in situ hybridization (not further specified); RNA (undefined); [2].
EX pulmonary valve,,,fetal; detectable; RNA-in situ hybridization (not further specified); RNA (undefined); [2].
EX umbilical artery,vascular smooth muscle cell,,fetal; detectable; RNA-in situ hybridization (not further specified); RNA (undefined); [2].
EX vena cava,vascular smooth muscle cell,,fetal; low; RNA-in situ hybridization (not further specified); RNA (undefined); [2].
EX ventricle of heart (right and left),,,fetal; detectable; RNA-in situ hybridization (not further specified); RNA (undefined); [2].
EX visceral pericardium,,,fetal; detectable; RNA-in situ hybridization (not further specified); RNA (undefined); [2].
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IN T20056 Mel-18; mouse, Mus musculus.
IN T00752 Sp1; mouse, Mus musculus.
IN T09343 SRF; human, Homo sapiens.
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MX M00462 V$GATA6_01.
MX M02757 V$GATA6_04.
MX M02861 V$GATA6_05.
MX M05605 V$GATA6_06.
MX M03216 V$GATA6_Q5.
MX M00789 V$GATA_Q6.
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BS R16353.
BS R60592.
BS R38456.
BS R60195.
BS R60203.
BS R65583.
BS R65585.
BS R65586.
BS R65587.
BS R65588.
BS R65589.
BS R65590.
BS R22886.
BS R69909.
BS R69910.
BS R37047.
BS R69495.
BS R69496.
BS R65610.
BS R65611.
BS R40123.
BS R35557.
BS R35558.
BS R69912.
BS R69913.
BS R69915.
BS R69916.
BS R42140.
BS R65591.
BS R65592.
BS R65593.
BS R13145.
BS R32079.
BS R32131.
BS R32133.
BS R68668.
BS R68670.
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DR TRANSPATH: MO000026662.
DR UniProtKB: Q61169;
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RN [1]; RE0013563.
RX PUBMED: 8660897.
RA Morrisey E. E., Ip H. S., Lu M. M., Parmacek M. S.
RT GATA-6: a zinc finger transcription factor that is expressed in multiple cell lineages derived from lateral mesoderm.
RL Dev. Biol. 177:309-322 (1996).
RN [2]; RE0013564.
RX PUBMED: 8812463.
RA Narita N., Heikinheimo M., Bielinska M., White R. A., Wilson D. B.
RT The gene for transcription factor GATA-6 resides on mouse chromosome 18 and is expressed in myocardium and vascular smooth muscle.
RL Genomics 36:345-348 (1996).
RN [3]; RE0051927.
RX PUBMED: 17213386.
RA Sher N., Yivgi-Ohana N., Orly J.
RT Transcriptional regulation of the cholesterol side chain cleavage cytochrome P450 gene (CYP11A1) revisited: binding of GATA, cyclic adenosine 3',5'-monophosphate response element-binding protein and activating protein (AP)-1 proteins to a distal novel cluster of cis-regulatory elements potentiates AP-2 and steroidogenic factor-1-dependent gene expression in the rodent placenta and ovary.
RL Mol. Endocrinol. 21:948-962 (2007).
RN [4]; RE0065693.
RX PUBMED: 18768929.
RA Zhou B., Francis T. A., Yang H., Tseng W., Zhong Q., Frenkel B., Morrisey E. E., Ann D. K., Minoo P., Crandall E. D., Borok Z.
RT GATA-6 mediates transcriptional activation of aquaporin-5 through interactions with Sp1.
RL Am. J. Physiol. Cell Physiol. 295:C1141-50 (2008).
RN [5]; RE0066629.
RX PUBMED: 15550397.
RA Yin F., Herring B. P.
RT GATA-6 can act as a positive or negative regulator of smooth muscle-specific gene expression.
RL J. Biol. Chem. 280:4745-4752 (2005).
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