AC T03337
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ID T03337
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DT 17.05.2000 (created); rio.
DT 20.06.2014 (updated); pro.
CO Copyright (C), QIAGEN.
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FA HOXA13
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SY Hox-1.10.
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OS mouse, Mus musculus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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GE G006212 Hoxa13.
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CL C0006; homeo; 3.1.1.8.13.
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SF phenotype of hypodactyly (hd) mice: Hd/+ mice have a shortened digit 1 on all four limbs but are otherwise normal and fertile whereas Hd/Hd animals usually die in utero - those that are born have a single digit on each limb and are infertile [1];
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FF hypodactyly (Hd) is caused by a deletion in the first exon and is also observed in HOXD13 deficient mice [1];
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IN T03388 meis1-a; mouse, Mus musculus.
IN T03389 meis1-b; mouse, Mus musculus.
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MX M01292 V$HOXA13_01.
MX M01297 V$HOXA13_02.
MX M01430 V$HOXA13_03.
MX M07456 V$HOXA913_Q4.
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BS R62480.
BS R62487.
BS R62488.
BS R18926.
BS R18927.
BS R18928.
BS R18930.
BS R18929.
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DR TRANSPATH: MO000027275.
DR PATHODB: MT010472.
DR UniProtKB: Q62424;
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RN [1]; RE0014509.
RX PUBMED: 8673126.
RA Mortlock D. P., Post L. C., Innis J. W.
RT The molecular basis of hypodactyly (Hd): a deletion in Hoxa 13 leads to arrest of digital arch formation
RL Nat. Genet. 13:284-289 (1996).
RN [2]; RE0064941.
RX PUBMED: 15617687.
RA Williams T. M., Williams M. E., Innis J. W.
RT Range of HOX/TALE superclass associations and protein domain requirements for HOXA13:MEIS interaction.
RL Dev. Biol. 277:457-471 (2005).
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