AC T03881
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ID T03881
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DT 29.09.2000 (created); rio.
DT 29.08.2008 (updated); tgo.
CO Copyright (C), QIAGEN.
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FA ATBF1
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SY AT motif binding factor 1.
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OS mouse, Mus musculus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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GE G004482 Zfhx3.
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HO zfh-2 (Drosophila) T00920.
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CL C0006; homeo; 3.1.8.4.2.
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SF 23 zinc finger motifs and 4 homeo domains with 94-100% identity to human ATBF1-A T01665 (94% overall identity) [1];
SF RA (retinoic acid) can induce high levels of expression in P19 cells [3];
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CP (cell lines:) high levels in Hepa1-6 hepatoma and XBF1 teratoma cells [1].
EX brain,,,adult; low; Northern blot; total RNA; [1].
EX brain,,,adult; medium; RNA-in situ hybridization (not further specified); RNA (undefined); [1].
EX heart,,,adult; high; RNA-in situ hybridization (not further specified); RNA (undefined); [1].
EX heart,,,adult; low; Northern blot; total RNA; [1].
EX intestinal crypts,,,adult; detectable; RNA-in situ hybridization (not further specified); RNA (undefined); [2].
EX intestinal villi,,,adult; detectable; RNA-in situ hybridization (not further specified); RNA (undefined); [2].
EX kidney (right and left),,,adult; low; Northern blot; total RNA; [1].
EX kidney (right and left),,,adult; medium; RNA-in situ hybridization (not further specified); RNA (undefined); [1].
EX liver,,,adult; none; Northern blot; total RNA; [1].
EX liver,,,adult; very low; RNA-in situ hybridization (not further specified); RNA (undefined); [1].
EX lung,,,adult; high; RNA-in situ hybridization (not further specified); RNA (undefined); [1].
EX lung,,,adult; low; Northern blot; total RNA; [1].
EX spleen,,,adult; medium; RNA-in situ hybridization (not further specified); RNA (undefined); [1].
EX spleen,,,adult; none; Northern blot; total RNA; [1].
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FF may play a role in neuronal differentiation and development of the mammalian CNS [1] [3];
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MX M00616 V$AFP1_Q6.
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DR TRANSPATH: MO000027805.
DR UniProtKB: Q61329;
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RN [1]; RE0015113.
RX PUBMED: 8654949.
RA Ido A., Miura Y., Watanabe M., Sakai M., Inoue Y., Miki T., Hashimoto T., Morinaga T., Nishi S., Tamaoki T.
RT Cloning of the cDNA encoding the mouse ATBF1 transcription factor
RL Gene 168:227-231 (1996).
RN [2]; RE0015133.
RX PUBMED: 10623580.
RA Kataoka H., Joh T., Miura Y., Tamaoki T., Senoo K., Ohara H., Nomura T., Tada T., Asai K., Kato T., Itoh M.
RT AT motif binding factor 1-A (ATBF1-A) negatively regulates transcription of the aminopeptidase N gene in the crypt-villus axis of small intestine
RL Biochem. Biophys. Res. Commun. 267:91-95 (2000).
RN [3]; RE0015179.
RX PUBMED: 8174773.
RA Ido A., Miura Y., Tamaoki T.
RT Activation of ATBF1, a multiple-homeodomain zinc-finger gene, during neuronal differentiation of murine embryonal carcinoma cells
RL Dev. Biol. 163:184-187 (1994).
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//