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TRANSFAC FACTOR TABLE, Release 2017.2 - public - 2017-06-30, (C) QIAGEN


AC T04129 XX ID T04129 XX DT 20.12.2000 (created); rio. DT 29.04.2010 (updated); jig. CO Copyright (C), QIAGEN. XX FA meis1-c XX SY myeloid ecotropic viral integration site 1c. XX OS mouse, Mus musculus OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae XX GE G014347 Meis1. XX CL C0006; homeo. XX SZ 341 AA; 37.5 kDa (cDNA) (calc.). XX SQ MAQRYDDLPHYGGMDGVGIPSTMYGDPHAARSMQPVHHLNHGPPLHSHQYPHTAHTNAMA SQ PSMGSSVNDALKRDKDAIYGHPLFPLLALIFEKCELATCTPREPGVAGGDVCSSESFNED SQ IAVFAKQIRAEKPLFSSNPELDNLMIQAIQVLRFHLLELEKPSWNRDHDDTASTRSGGTP SQ GPSSGGHTSHSGDNSSEQGDGLDNSVASPSTGDDDDPDKDKKRHKKRGIFPKVATNIMRA SQ WLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRAVSQGTPYN SQ PDGQPMGGFVMDGQQHMGIRAPGPMSGMGMNMGMEGQWHYM XX SC sequence taken from ref. [2] XX FT 1 299 PF00478; IMP dehydrogenase / GMP reductase domain. FT 71 100 HR1 domain [2]. FT 135 161 HR2 domain (partial) [2]. FT 221 284 PS50071; HOMEOBOX_2. FT 223 288 SM00389; HOX_1. FT 224 283 PF00046; Homeobox domain. XX SF TALE (three amino acid loop extension) homeo domain superclass [1]; SF cooperative binding with Pbx-1 T01481T02087, meis1-c is positioned 3' to Pbx-1 [2]; SF N-terminal region (HR1 and HR2) shares homology with PKNOX1 T04121 and mediates binding to Pbx-1 T01481 T02087 [2]; XX MX M00420 V$MEIS1AHOXA9_01. MX M00421 V$MEIS1BHOXA9_02. MX M00419 V$MEIS1_01. MX M01419 V$MEIS1_02. XX BS R09696. XX DR TRANSPATH: MO000028032. XX RN [1]; RE0014544. RX PUBMED: 9336443. RA Burglin T. R. RT Analysis of TALE superclass homeobox genes (MEIS, PBC, KNOX, Iroquois, TGIF) reveals a novel domain conserved between plants and animals RL Nucleic Acids Res. 25:4173-4180 (1997). RN [2]; RE0015495. RX PUBMED: 9405651. RA Knoepfler P. S., Calvo K. R., Chen H., Antonarakis S. E., Kamps M. P. RT Meis1 and pKnox1 bind DNA cooperatively with Pbx1 utilizing an interaction surface disrupted in oncoprotein E2a-Pbx1 RL Proc. Natl. Acad. Sci. USA 94:14553-14558 (1997). XX //