AC T04288
XX
ID T04288
XX
DT 02.02.2001 (created); rio.
DT 07.04.2010 (updated); jig.
CO Copyright (C), QIAGEN.
XX
FA NKX3A-V2
XX
SY Nkx-3.1; NKX3.1; NKX3A v2.
XX
OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
XX
GE G004029 NKX3-1; HGNC: NKX3-1.
XX
HO NK-3 T03612 Drosophila.
XX
CL C0006; homeo; 3.1.2.16.1.2.
XX
SZ 185 AA; 21.1 kDa (cDNA) (calc.).
XX
SQ MLRVPEPEPEPEPEGGRSRAGAQNDQLSTGPRAAPEEAETLAETEPERHLGSYLLDSENT
SQ SGALPRLPQTPKQPQKRSRAAFSHTQVIELERKFSHQKYLSAPERAHLAKNLKLTETQVK
SQ IWFQNRRYKTKRKQLSSELGDLEKHSSLPALKEEAFSRASLVSVYNSYPYYPYLYCVGSW
SQ SPAFW
XX
SC translated from EMBL #AF249670
XX
FT 73 133 
PS50071; HOMEOBOX_2.
FT 75 137 
SM00389; HOX_1.
FT 76 132 
PF00046; Homeobox domain.
XX
SF at least 5 different splice variants: NKX3A T04255, NKX3A v1T04287, NKX3A v2 T04288, NKX3A v3 T04289 and NKX3A v4 T04290 [1];
SF androgens and estradiol but not progesterone can increase expression [1];
XX
FF may have important regulatory roles during prostate cancer progression [1];
XX
MX M00451 V$NKX3A_01.
MX M01383 V$NKX3A_02.
MX M03833 V$NKX3A_Q3.
XX
DR TRANSPATH: MO000028151.
DR EMBL: AF249670;
DR UniProtKB: Q99801-2;
XX
RN [1]; RE0015706.
RX PUBMED: 11137288.
RA Korkmaz K. S., Korkmaz C. G., Ragnhildstveit E., Kizildag S., Pretlow T. G., Saatcioglu F.
RT Full-length cDNA sequence and genomic organization of human NKX3A - alternative forms and regulation by both androgens and estrogens
RL Gene 260:25-36 (2000).
XX
//