AC T04371
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ID T04371
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DT 07.03.2001 (created); rio.
DT 06.04.2009 (updated); ach.
CO Copyright (C), QIAGEN.
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FA EHAND
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SY eHand; heart- and neural crest derivatives-expressed 1; Hxt; Th1; Thing1.
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OS chick, Gallus gallus
OC eukaryota; animalia; metazoa; chordata; vertebrata; aves; neornithes; neognathae; galliformes; phasianidae
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CL C0010; bHLH.
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SZ 202 AA; 22.7 kDa (cDNA) (calc.).
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SQ MNLVGGYQHHHHHHHHHHMLHEPFLFGPAARCHQERAYFPGWVLNPAEVTPELHGQSPAY
SQ GPAEFGSGGAGRLEALSGRLGRRKGVGGPKKERRRTESINSAFAELRECIPNVPADTKLS
SQ KIKTLRLATSYIAYLMEVLARDSQPGEPEGFKAELKKADGRENKRKRETQPEVYSQPLAH
SQ GEKKLKGRTGWPQQVWALELNP
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SC translated from EMBL #U40041
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FT 81 136 
PS50888; HLH.
FT 84 136 
PF00010; Helix-loop-helix DNA-binding domain.
FT 89 141 
SM00353; finulus.
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SF 73% amino acid identity to murine EHAND T01569 [1];
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CP (stage 8-9:) cardiac crescent, (stage 10:) cardiac tube, sinus venosus, (stage 15-20:) atria, left ventricle, bulbus cordis, truncus arteriosus, branchial arches [1].
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FF EHAND together with Hand2 T04372 may play redundant roles in regulation of heart development especially cardiac looping [1];
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MX M01034 V$EBOX_Q6_01.
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DR TRANSPATH: MO000028228.
DR EMBL: U40041;
DR UniProtKB: Q90691;
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RN [1]; RE0006279.
RX PUBMED: 8533092.
RA Srivastava D., Cserjesi P., Olson E. N.
RT A subclass of bHLH proteins required for cardiac morphogenesis
RL Science 270:1995-1999 (1995).
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