AC T04374
XX
ID T04374
XX
DT 08.03.2001 (created); rio.
DT 13.01.2010 (updated); jig.
CO Copyright (C), QIAGEN.
XX
FA HAND2
XX
SY dHand; heart- and neural crest derivatives-expressed 2; Th2; Thing2.
XX
OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
XX
GE G002335 HAND2; HGNC: HAND2.
XX
CL C0010; bHLH; 1.2.3.2.4.
XX
SF 100%, 97% and 92% amino acid identity to rat, mouse T04370 and chicken T04372 Hand2 respectively [1];
XX
CN NT2 teratocarcinoma cells.
EX brain,,,adult; none; Northern blot; mRNA (poly-A); [1].
EX heart,,,adult; very high; Northern blot; mRNA (poly-A); [1].
EX kidney (right and left),,,adult; none; Northern blot; mRNA (poly-A); [1].
EX liver,,,adult; none; Northern blot; mRNA (poly-A); [1].
EX lung (right and left),,,adult; none; Northern blot; mRNA (poly-A); [1].
EX muscles,,,adult; none; Northern blot; mRNA (poly-A); [1].
EX pancreas,,,adult; none; Northern blot; mRNA (poly-A); [1].
EX placenta,,,adult; none; Northern blot; mRNA (poly-A); [1].
XX
FF may have an important role in cardiac development [1];
XX
MX M01034 V$EBOX_Q6_01.
XX
DR TRANSPATH: MO000028231.
DR UniProtKB: P61296;
XX
RN [1]; RE0015876.
RX PUBMED: 9878849.
RA Russell M. W., Kemp P., Wang L., Brody L. C., Izumo S.
RT Molecular cloning of the human HAND2 gene.
RL Biochim. Biophys. Acta 1443:393-399 (1998).
RN [2]; RE0025287.
RX PUBMED: 14506227.
RA Rychlik J. L., Gerbasi V., Lewis E. J.
RT The interaction between dHAND and Arix at the dopamine beta-hydroxylase promoter region is independent of direct dHAND binding to DNA.
RL J. Biol. Chem. 278:49652-49660 (2003).
XX
//