AC T04679
XX
ID T04679
XX
DT 27.08.2001 (created); rio.
DT 04.04.2005 (updated); elf.
CO Copyright (C), QIAGEN.
XX
FA dri
XX
SY dead ringer; retained; retn.
XX
OS fruit fly, Drosophila melanogaster
OC eukaryota; animalia; metazoa; arthropoda; insecta; diptera; drosophiloidea; drosophilidae
XX
GE G002604 retn.
XX
CL C0048; ARID.
XX
SZ 901 AA; 96.0 kDa (calc.).
XX
SQ MDCSGRSTSNIERDSDLGDDLSHGDRTDDEMRDCDSVDGEHHQLSAKAAIAARLSHTVSG
SQ GGGSFASPEPQTELPLSHHHQLPPNHPLNALGSFMGIGGLHSIPNLQHSDVLEKLKMQVR
SQ DMKVGLMEQDYAAAAHAAAFGANMLPTTISSGFPLPHNSVAFGHVTSAPSGGNGSSYNGG
SQ TTPTNSSNSNATTNGGGTAGPGGTGGSGGGGAGGGGGGGGGVGGHQFSFASPTAAPSGKE
SQ ANSASNSSTSSEASNSSQQNNGWSFEEQFKQVRQLYEINDDPKRKEFLDDLFSFMQKRGT
SQ PINRLPIMAKSVLDLYELYNLVIARGGLVDVINKKLWQEIIKGLHLPSSITSAAFTLRTQ
SQ YMKYLYPYECEKKNLSTPAELQAAIDGNRREGRRSSYGQYEAMHNQMPMTPISRPSLPGG
SQ MQQMSPLALVTHAAVANNQQAQAAAAAAAAHHRLMGAPAFGQMPNLVKQEIESRMMEYLQ
SQ LIQAKKEQGMPPVLGGNHPHQQQHSQQQQQQHHHQQQQQQSQQQHHLQQQRQRSQSPDLS
SQ KHEALSAQVALWHMYHNNNSPPGSAHTSPQQREALNLSDSPPNLTNIKREREREPTPEPV
SQ DQDDKFVDQPPPAKRVGSGLLPPGFPANFYLNPHNMAAVAAAAGFHHPSMGHQQDAASEG
SQ EPEDDYAHGEHNTTGNSSSMHDDSEPQQMNGHHHHQTHHLDKSDDSAIENSPTTSTTTGG
SQ SVGHRHSSPVSTKKKGGAKPQSGGKDLPTEDKDASSSGKLNPLETLSLLSGMQFQVARNG
SQ TGDNGEPQLIVNLELNGVKYSGVLVANVPLSQSETRTSSPCHAEAPTVEEEKDEEEEEEE
SQ EPKAAEEESHRSPVKQENEDADQDMEGSEVLLNGGASAVGGAGAGVGVGVGVPLLKDAVV
SQ S
XX
SC translated from EMBL #U62542
XX
FT 35 558 PF00478; IMP dehydrogenase / GMP reductase domain.
FT 278 388 PF01388; ARID/BRIGHT DNA binding domain.
FT 281 373 PS51011; ARID.
FT 282 374 SM00501; bright_3.
XX
SF the consensus binding site is similar to that of many homeo domain factors [1];
XX
CP maternal expressed, (2-3h:) three broad bands (termini and central), (3-5h:) predominantly mesoderm, (after gastrulation:) ubiquitous, (stage 15-16:)pharyngeal muscles, amnioserosa, hindgut, ring gland, clypeolabrum, midgut-hindgut junction, brain, salivary ducts [1].
XX
FF regulatory roles during development [1];
FF Dri plays an important role in converting Dorsal T00196 from an activator into a repressor [2];
XX
IN T02451 groucho; fruit fly, Drosophila melanogaster.
XX
MX M00455 I$DRI_01.
XX
BS R10411.
BS R10412.
BS R10413.
BS R10414.
BS R10415.
BS R10416.
BS R10417.
BS R10418.
BS R10419.
BS R10420.
BS R10421.
BS R10422.
BS R10423.
BS R10424.
BS R10425.
BS R10426.
BS R10427.
BS R10428.
BS R10429.
BS R10430.
BS R10431.
BS R10432.
BS R10433.
BS R10434.
BS R10435.
BS R10436.
BS R10437.
BS R10438.
BS R10439.
BS R10440.
BS R10441.
BS R10442.
BS R10443.
BS R10444.
BS R10445.
BS R10446.
BS R10447.
BS R10448.
BS R10449.
BS R10450.
BS R10451.
BS R10452.
BS R16491.
BS R16488.
XX
DR TRANSPATH: MO000028502.
DR EMBL: U62542;
DR UniProtKB: Q24573;
DR FLYBASE: FBgn0004795; dri, retn.
XX
RN [1]; RE0012299.
RX PUBMED: 8622680.
RA Gregory S. L., Kortschak R. D., Kalionis B., Staint R.
RT Characterization of the dead ringer gene identifies a novel, highly conserved family of sequence-specific DNA-binding proteins
RL Mol. Cell. Biol. 16:792-799 (1996).
RN [2]; RE0025509.
RX PUBMED: 9774673.
RA Valentine S. A., Chen G., Shandala T., Fernandez J., Mische S., Saint R., Courey A. J.
RT Dorsal-mediated repression requires the formation of a multiprotein repression complex at the ventral silencer.
RL Mol. Cell. Biol. 18:6584-6594 (1998).
XX
//