AC T04812
XX
ID T04812
XX
DT 05.10.2001 (created); mas.
DT 04.02.2009 (updated); mkl.
CO Copyright (C), QIAGEN.
XX
FA FOXP1b
XX
SY forkhead-related transcription factor 1; FOXP1.
XX
OS mouse, Mus musculus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
XX
GE G002814 Foxp1.
XX
CL C0023; fork head.
XX
SZ 641 AA; 71.6 kDa (cDNA) (calc.).
XX
SQ MMQESGSETKSNGSAIQNGSSGGNHLLECGALRDTRSNGEAPAVDLGAADLAHVQQQQQQ
SQ ALQVARQLLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQVSGLKSPKRNDKQ
SQ PALQVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQVLLQQQQALMLQQQLQEFYKKQQ
SQ EQLQLQLLQQQHAGKQPKEQQVATQQLAFQQQLLQMQQLQQQHLLSLQRQGLLTIQPGQP
SQ ALPLQPLAQGMIPTELQQLWKEVTSAHTAEETTSSNHSSLDLTSTCVSSSAPSKSSLIMN
SQ PHASTNGQLSVHTPKRESLSHEEHPHSHPLYGHGVCKWPGCEAVCDDFPAFLKHLNSEHA
SQ LDDRSTAQCRVQMQVVQQLELQLAKDKERLQAMMTHLHVKSTEPKAAPQPLNLVSSVTLS
SQ KSASEASPQSLPHTPTTPTAPLTPVTQGPSVITTTSMHTVGPIRRRYSDKYNVPISSADI
SQ AQNQEFYKNAEVRPPFTYASLIRQAILESPEKQLTLNEIYNWFTRMFAYFRRNAATWKAS
SQ MAENSIPLYTTASMGNPTLGSLASAIREELNGAMEHTNSNESDSSPGRSPMQAVHPIHVK
SQ EEPLDPEEAEGPLSLVTTANHSPDFDHDRDYEDEPVNEDME
XX
SC translated from EMBL #AF339104
XX
FT 55 230 
glutamine-rich region region [1].
FT 97 433 
PF00478; IMP dehydrogenase / GMP reductase domain.
FT 336 359 
putative zinc-finger region [1].
FT 361 426 
dimerization domain [2].
FT 376 397 
leucine zipper (VL3) [2].
FT 485 538 
winged-helix/forhead domain (C-terminal truncated) [1].
FT 491 579 
SM00339; forkneu4.
FT 493 544 
PS50039; FORK_HEAD_3.
FT 493 580 
PF00250; Fork head domain.
FT 507 516 
PF00904; Involucrin repeat.
FT 539 539 insertion of 64 amino acids in isoforms T04811 and T04813 [1].
XX
SF member of a new subfamily of winged-helix/forkhead DNA binding domain transcription factors [1];
SF 3 isoforms exist that are most probably caused by differential splicing: T04811, T04812, T04813 [1];
SF lacks C-terminal portion of winged-helix/forkhead DNA binding domain that is present in isoform T04811 [1];
SF existence of drosophila protein with high similarity in forkhead domain [1];
XX
CP (high:) spleen, (low:) widely expressed (mRNA) [2].
XX
MX M00987 V$FOXP1_01.
XX
DR TRANSPATH: MO000028619.
DR EMBL: AF339104;
DR UniProtKB: P58462-2;
XX
RN [1]; RE0016948.
RX PUBMED: 11358962.
RA Shu W., Yang H., Zhang L., Lu M. M., Morrisey E. E.
RT Characterization of a new subfamily of winged-helix/forkhead (Fox) genes that are expressed in the lung and act as transcriptional repressors
RL J. Biol. Chem. 276:27488-27497 (2001).
RN [2]; RE0024165.
RX PUBMED: 12692134.
RA Wang B., Lin D., Li C., Tucker P.
RT Multiple domains define the expression and regulatory properties of Foxp1 forkhead transcriptional repressors.
RL J. Biol. Chem. 278:24259-24268 (2003).
XX
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