AC T04876
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ID T04876
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DT 20.11.2001 (created); rge.
DT 10.11.2006 (updated); kau.
CO Copyright (C), QIAGEN.
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FA TEF-xbb1
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SY Thyrotroph Embryonic Factor.
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G002909 TEF; HGNC: TEF.
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CL C0008; bZIP.
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SZ 261 AA; 29.2 kDa (cDNA) (calc.).
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SQ MENPPREARLDEEKGKEKLEEDEAAAASTMAVSASLMPPIWDKTIPYDGESFHLEYMDLD
SQ EFLLENGIPASPTHLAHNLLLPVAELEGKESASSSTASPPSSSTAIFQPSETVSSTESSL
SQ EKERETPSPIDPNCVEVDVNFNPDPADLVLSSVPGGELFNPRKHKFAEEDLKPQPMIKKA
SQ KKVFVPDEQKDEKYWTRRKKNNVAAKRSRDARRLKENQITIRAAFLEKENTALRTEVAEL
SQ RKEVGKCKTIVSKYETKYGPL
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SC translated from EMBL #U06935
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FT 189 253 SM00338; brlzneu.
FT 190 243 PF07716; Basic region leucine zipper.
FT 191 254 PS50217; BZIP.
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SF TEF-xbb1 bound preferentially to the consensus sequence GTTACGTAAT(binding site selection assay) [2];
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CP lung, liver, spleen, and kidney [1].
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IN T18808 B-ATF; human, Homo sapiens.
IN T09526 CHOP-10-isoform1; human, Homo sapiens.
IN T09554 DBP; human, Homo sapiens.
IN T09569 Hlf-isoform1; human, Homo sapiens.
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MX M00672 V$TEF_Q6.
MX M00228 V$VBP_01.
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DR TRANSPATH: MO000028670.
DR EMBL: U06935;
DR EMBL: U44059;
DR UniProtKB: Q10587;
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RN [1]; RE0017142.
RX PUBMED: 7835883.
RA Khatib Z. A., Inaba T., Valentine M., Look A. T.
RT Chromosomal localization and cDNA cloning of the human DBP and TEF genes
RL Genomics 23:344-351 (1994).
RN [2]; RE0017147.
RX PUBMED: 8639829.
RA Hunger S. P., Li S., Fall M. Z., Naumovski L., Cleary M. L.
RT The proto-oncogene HLF and the related basic leucine zipper protein TEF display highly similar DNA-binding and transcriptional regulatory properties
RL Blood 87:4607-4617 (1996).
RN [3]; RE0048287.
RX PUBMED: 12805554.
RA Newman J. R., Keating A. E.
RT Comprehensive identification of human bZIP interactions with coiled-coil arrays.
RL Science 300:2097-2101 (2003).
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