AC T09526
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ID T09526
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DT 30.10.2006 (created); kau.
CO Copyright (C), QIAGEN.
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FA CHOP-10-isoform1
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SY C/EBP homologous protein 10; CHOP; CHOP-10; GADD 153; growth arrest and DNA-damage-inducible gene 153.
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G009609 DDIT3; HGNC: DDIT3.
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CL C0008; bZIP.
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SZ 169 AA; 19.2 kDa (cDNA) (calc.).
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SQ MAAESLPFSFGTLSSWELEAWYEDLQEVLSSDENGGTYVSPPGNEEEESKIFTTLDPASL
SQ AWLTEEEPEPAEVTSTSQSPHSPDSSQSSLAQEEEEEDQGRTRKRKQSGHSPARAGKQRM
SQ KEKEQENERKVAQLAEENERLKQEIERLTREVEATRRALIDRMVNLHQA
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SC Swiss-Prot#P35638
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FT 96 161 SM00338; brlzneu.
FT 97 151 PF07716; Basic region leucine zipper.
FT 99 162 PS50217; BZIP.
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IN T00167 ATF-2-isoform1; human, Homo sapiens.
IN T01313 ATF-3-isoform1; human, Homo sapiens.
IN T09531 ATF-4; human, Homo sapiens.
IN T18798 ATFa-isoform3; human, Homo sapiens.
IN T18808 B-ATF; human, Homo sapiens.
IN T18804 batf3; human, Homo sapiens.
IN T08776 c-Fos; human, Homo sapiens.
IN T00105 C/EBPalpha; human, Homo sapiens.
IN T06595 C/EBPbeta-FL; human, Homo sapiens.
IN T09139 C/EBPdelta; human, Homo sapiens.
IN T04883 C/EBPepsilon; human, Homo sapiens.
IN T10891 C/EBPepsilon; Mammalia.
IN T09524 C/EBPgamma; human, Homo sapiens.
IN T09550 CREBPA-Alpha; human, Homo sapiens.
IN T09554 DBP; human, Homo sapiens.
IN T09569 Hlf-isoform1; human, Homo sapiens.
IN T09572 MafG; human, Homo sapiens.
IN T09555 MafK; human, Homo sapiens.
IN T04876 TEF-xbb1; human, Homo sapiens.
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DR TRANSPATH: MO000089810.
DR EMBL: S40706; S40706.
DR UniProtKB: P35638; GA15_HUMAN.
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RN [1]; RE0001111.
RX PUBMED: 1400365.
RA Bartlett J. D., Luethy J. D., Carlson S. G., Sollott S. J., Holbrook N. J.
RT Calcium ionophore A23187 induces expression of the growth arrest and DNA damage inducible CCAAT/enhancer-binding protein (C/EBP)-related gene gadd153
RL J. Biol. Chem. 267:20465-20470 (1992).
RN [2]; RE0007049.
RX PUBMED: 8125258.
RA Barone M. V., Crozat A., Tabaee A., Philipson L., Ron D.
RT CHOP (GADD153) and its oncogenic variant, TLS-CHOP, have opposing effects on the induction of G1/S arrest
RL Genes Dev. 15:453-464 (1995).
RN [3]; RE0048287.
RX PUBMED: 12805554.
RA Newman J. R., Keating A. E.
RT Comprehensive identification of human bZIP interactions with coiled-coil arrays.
RL Science 300:2097-2101 (2003).
RN [4]; RE0066024.
RX PUBMED: 15308577.
RA Gery S., Park D. J., Vuong P. T., Chih D. Y., Lemp N., Koeffler H. P.
RT Retinoic acid regulates C/EBP homologous protein expression (CHOP), which negatively regulates myeloid target genes.
RL Blood 104:3911-3917 (2004).
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