AC T05012
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ID T05012
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DT 21.01.2002 (created); mas.
DT 15.06.2015 (updated); pro.
CO Copyright (C), QIAGEN.
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FA Elf-1
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SY E74-like factor 1; Elf1; ETS-related transcription factor ELF-1.
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OS mouse, Mus musculus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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GE G002964 Elf1.
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CL C0016; ETS; 3.5.2.3.1.
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CP (cell lines:) low levels in fibroblasts (NIH3T3), higher levels in B-cells (NFS112, NFS 70), T-cell (EL-4, RL-12), immature myeloid cells (FDCP-1), macrophages (BAC1.2F5) [1]; (adult:) bone marrow, spleen, kidney [1] [1].
CN (cell lines): PC12 (neuronal) [1]; (adult:) thymus, brain, heart muscle, skeletal muscle, pituitary gland, stomach, liver, intestine [1] [1].
EX bone marrow,,,adult; detectable; Northern blot; total RNA; [1].
EX brain,,,adult; none; Northern blot; total RNA; [1].
EX heart,,,adult; none; Northern blot; total RNA; [1].
EX intestine,,,adult; none; Northern blot; total RNA; [1].
EX kidney (right and left),,,adult; detectable; Northern blot; total RNA; [1].
EX kidney (right and left),renal tubular epithelial cell,,adult; detectable; RNAse protection assay; mRNA (poly-A); [2].
EX liver,,,adult; none; Northern blot; total RNA; [1].
EX muscles,,,adult; none; Northern blot; total RNA; [1].
EX pituitary gland of diencephalon,,,adult; none; Northern blot; total RNA; [1].
EX spleen,,,adult; detectable; Northern blot; total RNA; [1].
EX stomach,,,adult; none; Northern blot; total RNA; [1].
EX thymus,,,adult; none; Northern blot; total RNA; [1].
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FF obviously expression not only restricted to the lymphoid lineage [1];
FF seems to prefer similar DNA binding sites like two other ETS-family members Drosophila E74 T00208 and mouse Fli-1T01408 [1];
FF maybe regulates transcription of a broad range of genes [1];
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MX M01975 V$ELF1_01.
MX M07415 V$ELF1_07.
MX M07417 V$ELF1_Q4.
MX M01266 V$ELF1_Q5.
MX M00746 V$ELF1_Q6.
MX M00771 V$ETS_Q4.
MX M00971 V$ETS_Q6.
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BS R27476.
BS R28651.
BS R27475.
BS R25824.
BS R26370.
BS R68280.
BS R18615.
BS R19663.
BS R14427.
BS R22619.
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DR TRANSPATH: MO000028770.
DR UniProtKB: Q60775;
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RN [1]; RE0017447.
RX PUBMED: 8666284.
RA Davis J. N., Roussel M. F.
RT Cloning and expression of the murine Elf-1 cDNA
RL Gene 171:265-269 (1996).
RN [2]; RE0017525.
RX PUBMED: 8756667.
RA Oettgen P., Akbarali Y., Boltax J., Best J., Kunsch C., Libermann T. A.
RT Characterization of NERF, a novel transcription factor related to the Ets factor ELF-1
RL Mol. Cell. Biol. 16:5091-5106 (1996).
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//