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TRANSFAC FACTOR TABLE, Release 2017.2 - public - 2017-06-30, (C) QIAGEN


AC T05021 XX ID T05021 XX DT 15.02.2002 (created); mas. DT 06.10.2011 (updated); sla. CO Copyright (C), QIAGEN. XX FA nerf-isoform2 XX SY ELF2; ELF2B; new ets-related factor. XX OS human, Homo sapiens OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates XX GE G002979 ELF2; HGNC: ELF2. XX CL C0016; ETS; 3.5.2.3.2.1. XX SZ 521 AA; 56.1 kDa (calc.). XX SQ MATSLHEGPTNQLDLLIRAVEASVHSSNAHCTDKTIEAAEALLHMESPTCLRDSRSPEFI SQ HAAMRPDVITETVVEVSTEESEPMDTSPIPTSPDSHEPMKKKKVGRKPKTQQSPISNGSP SQ ELGIKKKPREGKGNTTYLWEFLLDLLQDKNTCPRYIKWTQREKGIFKLVDSKAVSKLWGK SQ HKNKPDMNYETMGRALRYYYQRGILAKVEGQRLVYQFKDMPKNIVVIDDDKSETCNEDLA SQ GTTDEKSLERVSLSAESLLKAASSVRSGKNSSPINCSRAEKGVARVVNITSPGHDASSRS SQ PTTTASVSATAAPRTVRVAMQVPVVMTSLGQKISTVAVQSVNAGAPLITSTSPTTATSPK SQ VVIQTIPTVMPASTENGDKITMQPAKIITIPATQLAQCQLQTKSNLTGSGSINIVGTPLA SQ VRALTPVSIAHGTPVMRLSMPTQQASGQTPPRVISAVIKGPEVKSEAVAKKQEHDVKTLQ SQ LVEEKPADGNKTVTHVVVVSAPSAIALPVTMKTEGLVTCEK XX SC Swiss-Prot#Q15723-2 XX FT 13 435 PF00478; IMP dehydrogenase / GMP reductase domain. FT 33 85 aspartate-/glutamate-rich region (13/53) [1]. FT 86 120 lysine-/histidine-rich region (7/35) [1]. FT 135 217 ets domain (DNA-binding) [1]. FT 135 220 PF00178; Ets-domain. FT 135 222 SM00413; etsneu2. FT 136 218 PS50061; ETS_DOMAIN_3. FT 138 208 PS50140; HSF_ETS. XX SF amino acid identity in DNA-binding domain (ETS domain) to other members of ETS-family of transcription factors: 90 % human ELF T01113 and 86 % to fruit fly E74 T00208, to other family members less than 50 % [1]; XX FF maybe repressor (at least of tyrosin kinase genes lyn and blk) [1]; FF seems to have similar affinities for several ETS DNA binding sites like ELF-1 T01113 [1]; XX MX M02054 V$ELF2_02. MX M00771 V$ETS_Q4. MX M00971 V$ETS_Q6. MX M00531 V$NERF_Q2. XX BS R02386. BS R12017. BS R12088. BS R12020. BS R03475. BS R12091. BS R12090. BS R12089. BS R12086. XX DR TRANSPATH: MO000028777. DR EMBL: U43189; DR UniProtKB: Q15723-2; XX RN [1]; RE0017525. RX PUBMED: 8756667. RA Oettgen P., Akbarali Y., Boltax J., Best J., Kunsch C., Libermann T. A. RT Characterization of NERF, a novel transcription factor related to the Ets factor ELF-1 RL Mol. Cell. Biol. 16:5091-5106 (1996). XX //