AC T05021
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ID T05021
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DT 15.02.2002 (created); mas.
DT 06.10.2011 (updated); sla.
CO Copyright (C), QIAGEN.
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FA nerf-isoform2
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SY ELF2; ELF2B; new ets-related factor.
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G002979 ELF2; HGNC: ELF2.
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CL C0016; ETS; 3.5.2.3.2.1.
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SZ 521 AA; 56.1 kDa (calc.).
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SQ MATSLHEGPTNQLDLLIRAVEASVHSSNAHCTDKTIEAAEALLHMESPTCLRDSRSPEFI
SQ HAAMRPDVITETVVEVSTEESEPMDTSPIPTSPDSHEPMKKKKVGRKPKTQQSPISNGSP
SQ ELGIKKKPREGKGNTTYLWEFLLDLLQDKNTCPRYIKWTQREKGIFKLVDSKAVSKLWGK
SQ HKNKPDMNYETMGRALRYYYQRGILAKVEGQRLVYQFKDMPKNIVVIDDDKSETCNEDLA
SQ GTTDEKSLERVSLSAESLLKAASSVRSGKNSSPINCSRAEKGVARVVNITSPGHDASSRS
SQ PTTTASVSATAAPRTVRVAMQVPVVMTSLGQKISTVAVQSVNAGAPLITSTSPTTATSPK
SQ VVIQTIPTVMPASTENGDKITMQPAKIITIPATQLAQCQLQTKSNLTGSGSINIVGTPLA
SQ VRALTPVSIAHGTPVMRLSMPTQQASGQTPPRVISAVIKGPEVKSEAVAKKQEHDVKTLQ
SQ LVEEKPADGNKTVTHVVVVSAPSAIALPVTMKTEGLVTCEK
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SC Swiss-Prot#Q15723-2
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FT 13 435 
PF00478; IMP dehydrogenase / GMP reductase domain.
FT 33 85 
aspartate-/glutamate-rich region (13/53) [1].
FT 86 120 
lysine-/histidine-rich region (7/35) [1].
FT 135 217 
ets domain (DNA-binding) [1].
FT 135 220 
PF00178; Ets-domain.
FT 135 222 
SM00413; etsneu2.
FT 136 218 
PS50061; ETS_DOMAIN_3.
FT 138 208 
PS50140; HSF_ETS.
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SF amino acid identity in DNA-binding domain (ETS domain) to other members of ETS-family of transcription factors: 90 % human ELF T01113 and 86 % to fruit fly E74 T00208, to other family members less than 50 % [1];
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FF maybe repressor (at least of tyrosin kinase genes lyn and blk) [1];
FF seems to have similar affinities for several ETS DNA binding sites like ELF-1 T01113 [1];
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MX M02054 V$ELF2_02.
MX M00771 V$ETS_Q4.
MX M00971 V$ETS_Q6.
MX M00531 V$NERF_Q2.
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BS R02386.
BS R12017.
BS R12088.
BS R12020.
BS R03475.
BS R12091.
BS R12090.
BS R12089.
BS R12086.
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DR TRANSPATH: MO000028777.
DR EMBL: U43189;
DR UniProtKB: Q15723-2;
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RN [1]; RE0017525.
RX PUBMED: 8756667.
RA Oettgen P., Akbarali Y., Boltax J., Best J., Kunsch C., Libermann T. A.
RT Characterization of NERF, a novel transcription factor related to the Ets factor ELF-1
RL Mol. Cell. Biol. 16:5091-5106 (1996).
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