AC T05022
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ID T05022
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DT 15.02.2002 (created); mas.
DT 20.05.2009 (updated); jag.
CO Copyright (C), QIAGEN.
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FA nerf-isoform3
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SY new ets-related factor.
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G002979 ELF2; HGNC: ELF2.
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CL C0016; ETS; 3.5.2.3.2.2.
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SZ 533 AA; 57.4 kDa (calc.).
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SQ MATSLHEGPTNQLDLLIRAVEASVHSSNAHCTDKTIEAAEALLHMESPTCLRDSRSPVEV
SQ FVPPCVSTPEFIHAAMRPDVITETVVEVSTEESEPMDTSPIPTSPDSHEPMKKKKVGRKP
SQ KTQQSPISNGSPELGIKKKPREGKGNTTYLWEFLLDLLQDKNTCPRYIKWTQREKGIFKL
SQ VDSKAVSKLWGKHKNKPDMNYETMGRALRYYYQRGILAKVEGQRLVYQFKDMPKNIVVID
SQ DDKSETCNEDLAGTTDEKSLERVSLSAESLLKAASSVRSGKNSSPINCSRAEKGVARVVN
SQ ITSPGHDASSRSPTTTASVSATAAPRTVRVAMQVPVVMTSLGQKISTVAVQSVNAGAPLI
SQ TSTSPTTATSPKVVIQTIPTVMPASTENGDKITMQPAKIITIPATQLAQCQLQTKSNLTG
SQ SGSINIVGTPLAVRALTPVSIAHGTPVMRLSMPTQQASGQTPPRVISAVIKGPEVKSEAV
SQ AKKQEHDVKTLQLVEEKPADGNKTVTHVVVVSAPSAIALPVTMKTEGLVTCEK
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SC Swiss-Prot#Q15723-3
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FT 13 447 
PF00478; IMP dehydrogenase / GMP reductase domain.
FT 33 85 
aspartate-/glutamate-rich region (9/53) [1].
FT 86 120 
lysine-/histidine-rich region (6/35) [1].
FT 147 229 
ets domain (DNA-binding) [1].
FT 147 232 
PF00178; Ets-domain.
FT 147 234 
SM00413; etsneu2.
FT 148 230 
PS50061; ETS_DOMAIN_3.
FT 150 220 
PS50140; HSF_ETS.
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SF amino acid identity in DNA-binding domain (ETS domain) to other members of ETS-family of transcription factors: 90 % human ELF T01113 and 86 % to fruit fly E74 T00208, to other family members less than 50 % [1];
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FF maybe repressor (at least of tyrosin kinase genes lyn and blk) [1];
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MX M00771 V$ETS_Q4.
MX M00971 V$ETS_Q6.
MX M00531 V$NERF_Q2.
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BS R12017.
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DR TRANSPATH: MO000028778.
DR EMBL: U43189;
DR UniProtKB: Q15723-3;
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RN [1]; RE0017525.
RX PUBMED: 8756667.
RA Oettgen P., Akbarali Y., Boltax J., Best J., Kunsch C., Libermann T. A.
RT Characterization of NERF, a novel transcription factor related to the Ets factor ELF-1
RL Mol. Cell. Biol. 16:5091-5106 (1996).
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