AC T05023
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ID T05023
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DT 15.02.2002 (created); mas.
DT 06.10.2011 (updated); sla.
CO Copyright (C), QIAGEN.
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FA nerf-isoform1
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SY ELF2; ELF2A; ets transcription factor; new ets-related factor.
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G002979 ELF2; HGNC: ELF2.
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CL C0016; ETS; 3.5.2.3.2.3.
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SZ 581 AA; 62.7 kDa (calc.).
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SQ MTSAVVDSGGTILELSSNGVENQEESEKVSEYPAVIVEPVPSARLEQGYAAQVLVYDDET
SQ YMMQDVAEEQEVETENVETVEASVHSSNAHCTDKTIEAAEALLHMESPTCLRDSRSPEFI
SQ HAAMRPDVITETVVEVSTEESEPMDTSPIPTSPDSHEPMKKKKVGRKPKTQQSPISNGSP
SQ ELGIKKKPREGKGNTTYLWEFLLDLLQDKNTCPRYIKWTQREKGIFKLVDSKAVSKLWGK
SQ HKNKPDMNYETMGRALRYYYQRGILAKVEGQRLVYQFKDMPKNIVVIDDDKSETCNEDLA
SQ GTTDEKSLERVSLSAESLLKAASSVRSGKNSSPINCSRAEKGVARVVNITSPGHDASSRS
SQ PTTTASVSATAAPRTVRVAMQVPVVMTSLGQKISTVAVQSVNAGAPLITSTSPTTATSPK
SQ VVIQTIPTVMPASTENGDKITMQPAKIITIPATQLAQCQLQTKSNLTGSGSINIVGTPLA
SQ VRALTPVSIAHGTPVMRLSMPTQQASGQTPPRVISAVIKGPEVKSEAVAKKQEHDVKTLQ
SQ LVEEKPADGNKTVTHVVVVSAPSAIALPVTMKTEGLVTCEK
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SC translated from EMBL #U43188
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FT 21 145 
aspartate-/glutamate-rich region (31/125) [1].
FT 52 495 
PF00478; IMP dehydrogenase / GMP reductase domain.
FT 146 180 
lysine-/histidine-rich region (7/35) [1].
FT 195 277 
ets domain (DNA-binding) [1].
FT 195 280 
PF00178; Ets-domain.
FT 195 282 
SM00413; etsneu2.
FT 196 278 
PS50061; ETS_DOMAIN_3.
FT 198 268 
PS50140; HSF_ETS.
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SF 44 % amino acid identity to human homolog ELF-1 T01113 [1];
SF amino acid identity in DNA-binding domain (ETS domain) to members of ETS-family of transcription factors: 90 % human ELF T01113 and 86 % to fruit fly E74 T00208, to other family members less than 50 % [1];
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FF activator [1];
FF seems to activate transcription of B-cell tyrosine kinases [1];
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MX M02054 V$ELF2_02.
MX M00771 V$ETS_Q4.
MX M00971 V$ETS_Q6.
MX M00531 V$NERF_Q2.
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BS R12017.
BS R36354.
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DR TRANSPATH: MO000028779.
DR EMBL: U43188;
DR UniProtKB: Q15723-1;
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RN [1]; RE0017525.
RX PUBMED: 8756667.
RA Oettgen P., Akbarali Y., Boltax J., Best J., Kunsch C., Libermann T. A.
RT Characterization of NERF, a novel transcription factor related to the Ets factor ELF-1
RL Mol. Cell. Biol. 16:5091-5106 (1996).
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