AC T05312
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ID T05312
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DT 25.10.2002 (created); oke.
DT 05.09.2013 (updated); uat.
CO Copyright (C), QIAGEN.
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FA CAR
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SY constitutive androstane receptor; constitutively active receptor; NR1I3; phenobarbital receptor.
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OS rat, Rattus norvegicus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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GE G004848 Nr1i3.
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CL C0002; CC (rec); 2.1.2.4.3.
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SF forms heterodimers with RXR-alpha [1];
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CP liver of male rats, in response to phenobarbital [2].
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FF activator as a heterodimer with RXR-alpha [1];
FF plays role in sexual dimorphic induction of CYP2B1 gene [2];
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IN T01345 RXR-alpha; human, Homo sapiens.
IN T04383 RXR-alpha; rat, Rattus norvegicus.
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MX M00966 V$DR3_Q4.
MX M00965 V$DR4_Q2.
MX M07280 V$NR1NR2_Q3.
MX M00964 V$PXR_Q2.
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BS R56213.
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DR TRANSPATH: MO000033917.
DR UniProtKB: Q9QUS1;
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RN [1]; RE0018105.
RX PUBMED: 11706036.
RA Kast H. R., Goodwin B., Tarr P. T., Jones S. A., Anisfeld A. M., Stoltz C. M., Tontonoz P., Kliewer S., Willson T. M., Edwards P. A.
RT Regulation of multidrug resistance-associated protein 2 (ABCC2) by the nuclear receptors pregnane X receptor, farnesoid X-activated receptor, and constitutive androstane receptor.
RL J. Biol. Chem. 277:2908-2915 (2002).
RN [2]; RE0018106.
RX PUBMED: 11160864.
RA Yoshinari K., Sueyoshi T., Moore R., Negishi M.
RT Nuclear receptor CAR as a regulatory factor for the sexually dimorphic induction of CYB2B1 gene by phenobarbital in rat livers.
RL Mol. Pharmacol. 59:278-284 (2001).
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