AC T05853
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ID T05853
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DT 05.02.2004 (created); elf.
DT 14.11.2013 (updated); yre.
CO Copyright (C), QIAGEN.
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FA Oligo1
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SY Bhlhb6; Olg-1; Olig1; oligodendrocyte transcription factor 1; Oligodendrocyte- specific bHLH transcription factor 1.
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OS mouse, Mus musculus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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GE G009162 Olig1.
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CL C0010; bHLH; 1.2.3.4.13.
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CP nervous tissue, ventral ventricular zone of spinal cord, oligodendrocyte progenitor [2]; mature oligodendrocytes [4]; nucleus of oligodendrocytes and their progenitors in postnatal day 1 mouse brain, Olig1 is almost completely cytoplasmic in the adult mouse brain [4]; corpus callosum, fornix, spinal cord [4] [2] [4].
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FF oligodendrogenesis [2];
FF repairing the types of lesions that occur in patients with multiple sclerosis [4];
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IN T00404 Id2; mouse, Mus musculus.
IN T01658 IDB4; mouse, Mus musculus.
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DR TRANSPATH: MO000039161.
DR UniProtKB: Q9JKN5;
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RN [1]; RE0023814.
RX PUBMED: 10719889.
RA Zhou Q., Wang S., Anderson D. J.
RT Identification of a novel family of oligodendrocyte lineage-specific basic helix-loop-helix transcription factors.
RL Neuron 25:331-343 (2000).
RN [2]; RE0023815.
RX PUBMED: 11091082.
RA Takebayashi H., Yoshida S., Sugimori M., Kosako H., Kominami R., Nakafuku M., Nabeshima Y.
RT Dynamic expression of basic helix-loop-helix Olig family members: implication of Olig2 in neuron and oligodendrocyte differentiation and identification of a new member, Olig3.
RL Mech. Dev. 99:143-148 (2000).
RN [3]; RE0025419.
RX PUBMED: 12042312.
RA Kim Y. S., Lewandoski M., Perantoni A. O., Kurebayashi S., Nakanishi G., Jetten A. M.
RT Identification of Glis1, a novel Gli-related, Kruppel-like zinc finger protein containing transactivation and repressor functions.
RL J. Biol. Chem. 277:30901-30913 (2002).
RN [4]; RE0025491.
RX PUBMED: 15604411.
RA Arnett H. A., Fancy S. P., Alberta J. A., Zhao C., Plant S. R., Kaing S., Raine C. S., Rowitch D. H., Franklin R. J., Stiles C. D.
RT bHLH transcription factor Olig1 is required to repair demyelinated lesions in the CNS.
RL Science 306:2111-2115 (2004).
RN [5]; RE0049142.
RX PUBMED: 15280210.
RA Samanta J., Kessler J. A.
RT Interactions between ID and OLIG proteins mediate the inhibitory effects of BMP4 on oligodendroglial differentiation.
RL Development 131:4131-4142 (2004).
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