AC T06590
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ID T06590
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DT 13.05.2005 (created); ili.
DT 02.12.2014 (updated); pro.
CO Copyright (C), QIAGEN.
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FA POU4F1
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SY Brn-3; Brn-3.0; Brn3; Brn3a; POU domain, class 4, transcription factor 1; POU4F1.
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OS mouse, Mus musculus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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GE G002463 Pou4f1.
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CL C0007; POU; 3.1.10.4.1.
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SF variants are T01877 and T01878;
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FF suggested to be important in regulating the expression of its proapoptotic targets Bax and Noxa during development [2];
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MX M00795 V$OCT_Q6.
MX M07060 V$POU4F1_Q3.
MX M03843 V$POU4F1_Q6.
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BS R34651.
BS R16704.
BS R65109.
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DR TRANSPATH: MO000054424.
DR UniProtKB: P17208;
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RN [1]; RE0004385.
RX PUBMED: 8290353.
RA Theil T., McLean-Hunter S., Zoernig M., Moeroey T.
RT Mouse BRN-3 family of POU transcription factors: a new aminoterminal domain is crucial for the oncogenic activity of BRN-3A
RL Nucleic Acids Res. 21:5921-5929 (1993).
RN [2]; RE0035170.
RX PUBMED: 15598651.
RA Hudson C. D., Morris P. J., Latchman D. S., Budhram-Mahadeo V. S.
RT Brn-3a transcription factor blocks p53-mediated activation of proapoptotic target genes Noxa and Bax in vitro and in vivo to determine cell fate.
RL J. Biol. Chem. 280:11851-11858 (2005).
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