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TRANSFAC FACTOR TABLE, Release 2017.2 - public - 2017-06-30, (C) QIAGEN


AC T08251 XX ID T08251 XX DT 04.11.2005 (created); elf. DT 16.04.2015 (updated); pro. CO Copyright (C), QIAGEN. XX FA LRF XX SY Factor binding IST protein 1; Factor that binds to inducer of short transcripts protein 1; FBI-1; FBI1; HIV-1 1st-binding protein 1; Leukemia/lymphoma related factor; Lrf; TIP21; TTF-I interacting peptide 21; ZBTB7; zinc finger and BTB domain containing 7; Zinc finger and BTB domain containing protein 7. XX OS human, Homo sapiens OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates XX GE G021445 ZBTB7A; HGNC: ZBTB7A. XX CL C0058; CH+BTB/POZ. XX SZ 584 AA; 61.4 kDa (cDNA) (calc.). XX SQ MAGGVDGPIGIPFPDHSSDILSGLNEQRTQGLLCDVVILVEGREFPTHRSVLAACSQYFK SQ KLFTSGAVVDQQNVYEIDFVSAEALTALMDFAYTATLTVSTANVGDILSAARLLEIPAVS SQ HVCADLLDRQILAADAGADAGQLDLVDQIDQRNLLRAKEYLEFFQSNPMNSLPPAAAAAA SQ ASFPWSAFGASDDDLDATKEAVAAAVAAVAAGDCNGLDFYGPGPPAERPPTGDGDEGDSN SQ PGLWPERDEDAPTGGLFPPPVAPPAATQNGHYGRGGEEEAASLSEAAPEPGDSPGFLSGA SQ AEGEDGDGPDVDGLAASTLLQQMMSSVGRAGAAAGDSDEESRADDKGVMDYYLKYFSGAH SQ DGDVYPAWSQKVEKKIRAKAFQKCPICEKVIQGAGKLPRHIRTHTGEKPYECNICKVRFT SQ RQDKLKVHMRKHTGEKPYLCQQCGAAFAHNYDLKNHMRVHTGLRPYQCDSCCKTFVRSDH SQ LHRHLKKDGCNGVPSRRGRKPRVRGGAPDPSPGATATPGAPAQPSSPDARRNGQEKHFKD SQ EDEDEDVASPDGLGRLNVAGAGGGGDSGGGPGAATDGNFTAGLA XX SC translated from EMBL:AF097916 XX FT 1 120 POZ domain [3]. FT 24 131 PF00651; BTB/POZ domain. FT 34 101 PS50097; BTB. FT 34 131 SM00225; BTB_4. FT 83 432 PF00478; IMP dehydrogenase / GMP reductase domain. FT 376 489 zinc finger (C2H2 type) [3]. FT 382 404 SM00355; c2h2final6. FT 382 409 PS50157; ZINC_FINGER_C2H2_2. FT 410 432 PF00096; zf-C2H2. FT 410 432 SM00355; c2h2final6. FT 410 437 PS50157; ZINC_FINGER_C2H2_2. FT 438 460 PF00096; zf-C2H2. FT 438 460 SM00355; c2h2final6. FT 438 465 PS50157; ZINC_FINGER_C2H2_2. FT 466 486 SM00355; c2h2final6. FT 466 490 PF00096; zf-C2H2. FT 466 501 PS50157; ZINC_FINGER_C2H2_2. FT 490 503 NLS (nuclear localization sequence) [3]. XX SF BTB/POZ-domain protein at the N-terminus, a protein-protein interaction domain, and zinc fingers at the C-terminus [1]; XX FF modulates HIV-1 Tat trans-activation and represses transcription of some cellular genes [1]; XX IN T08767 IkappaB-alpha; human, Homo sapiens. IN T00414 IkappaB-beta; human, Homo sapiens. IN T31905 KR3; Mammalia. IN T00594 RelA-p65-isoform1; human, Homo sapiens. XX MX M01100 V$LRF_Q2. MX M07387 V$LRF_Q3. MX M04617 V$LRF_Q6. XX BS R18501. BS R18502. BS R18483. BS R18484. BS R18486. BS R18487. BS R18488. BS R18489. BS R18490. BS R18491. BS R18492. BS R18493. BS R18494. BS R18495. BS R18496. BS R18497. BS R18500. BS R18499. BS R18482. BS R18481. BS R18480. BS R18479. BS R18478. BS R18477. BS R28003. BS R28239. BS R28240. BS R27849. BS R18503. BS R18504. BS R18505. BS R67233. BS R67235. BS R28122. BS R28125. BS R28127. BS R28128. BS R28139. BS R28140. BS R67227. BS R67231. BS R18506. BS R18507. BS R18508. BS R18509. XX DR TRANSPATH: MO000056499. DR EMBL: AF097916; AF097916. DR UniProtKB: O95365; ZBTB7_HUMAN. XX RN [1]; RE0035544. RX PUBMED: 12750370. RA Pessler F., Hernandez N. RT Flexible DNA binding of the BTB/POZ-domain protein FBI-1. RL J. Biol. Chem. 278:29327-29335 (2003). RN [2]; RE0047618. RX PUBMED: 15917220. RA Lee D. K., Kang J. E., Park H. J., Kim M. H., Yim T. H., Kim J. M., Heo M. K., Kim K. Y., Kwon H. J., Hur M. W. RT FBI-1 enhances transcription of the nuclear factor-kappaB (NF-kappaB)-responsive E-selectin gene by nuclear localization of the p65 subunit of NF-kappaB. RL J. Biol. Chem. 280:27783-27791 (2005). RN [3]; RE0063003. RX PUBMED: 12004059. RA Lee D. K., Suh D., Edenberg H. J., Hur M. W. RT POZ domain transcription factor, FBI-1, represses transcription of ADH5/FDH by interacting with the zinc finger and interfering with DNA binding activity of Sp1. RL J. Biol. Chem. 277:26761-26768 (2002). XX //