AC T08450
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ID T08450
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DT 23.01.2006 (created); rad.
DT 10.12.2012 (updated); prb.
CO Copyright (C), QIAGEN.
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FA DAX1
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SY AHCH; DAX-1; NR0B1; orphan nuclear receptor DAX-1.
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OS mouse, Mus musculus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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GE G002779 Nr0b1.
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CL C0002; CC (rec); 2.1.7.0.1.1.
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SZ 472 AA; 52.6 kDa (calc.).
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SQ MAGEDHPWQGSILYNLLMSAKQKHASQEEREVRLGAQCWGCACGAQPVLGGERLSGGQAR
SQ SLLYRCCFCGENHPRQGGILYSMLTNARQPSVATQAPRARFGAPCWGCACGSAEPLVGRE
SQ GLPAGQAPSLLYRCCFCGEEHPRQGSILYSLLTSAQQTHVSREAPEAHRRGEWWQLSYCT
SQ QSVGGPEGLQSTQAMAFLYRSYVCGEEQPQQISVASGTPVSADQTPATPQEQPRAPWWDA
SQ SPGVQRLITLKDPQVVCEAASAGLLKTLRFVKYLPCFQILPLDQQLVLVRSCWAPLLMLE
SQ LAQDHLHFEMMEIPETNTTQEMLTTRRQETEGPEPAEPQATEQPQMVSAEAGHLLPAAAV
SQ QAIKSFFFKCWSLNIDTKEYAYLKGTVLFNPDLPGLQCVKYIEGLQWRTQQILTEHIRMM
SQ QREYQIRSAELNSALFLLRFINSDVVTELFFRPIIGAVSMDDMMLEMLCAKL
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SC translated from EMBL #U41568
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FT 256 472 ligand-binding domain [2].
FT 258 442 SM00430; holi.
FT 261 467 PF00104; Ligand-binding domain of nuclear hormon.
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IN T00651 Oct3; mouse, Mus musculus.
IN T08497 TIF2; human, Homo sapiens.
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MX M01248 V$DAX1_01.
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DR TRANSPATH: MO000058140.
DR EMBL: U41568;
DR UniProtKB: Q61066;
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RN [1]; RE0068357.
RX PUBMED: 19528230.
RA Sun C., Nakatake Y., Akagi T., Ura H., Matsuda T., Nishiyama A., Koide H., Ko M. S., Niwa H., Yokota T.
RT Dax1 binds to Oct3/4 and inhibits its transcriptional activity in embryonic stem cells.
RL Mol. Cell. Biol. 29:4574-4583 (2009).
RN [2]; RE0016769.
RX PUBMED: 9566914.
RA Crawford P. A., Dorn C., Sadovsky Y., Milbrandt J.
RT Nuclear receptor DAX-1 recruits nuclear receptor corepressor N-CoR to steroidogenic factor 1
RL Mol. Cell. Biol. 18:2949-2956 (1998).
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