AC T08465
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ID T08465
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DT 23.01.2006 (created); jag.
CO Copyright (C), QIAGEN.
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FA C/EBPalpha-isoform1
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SY BPc; C/EBP; C/EBP alpha; C/EBPalpha; CBP; CCAAT Enhancer Binding Protein alpha; CCAAT/enhancer binding protein alpha; CEBPA; EBP20.
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G001170 CEBPA; HGNC: CEBPA.
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CL C0008; bZIP.
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SZ 358 AA; 37.6 kDa (cDNA) (calc.).
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SQ MESADFYEAEPRPPMSSHLQSPPHAPSSAAFGFPRGAGPPKPPAPPAAPEPLGGICEHET
SQ SIDISAYIDPAAFNDEFLADLFQHSRQQEKAKAAVGPTGGGGGGDFDYPGAPAGPGGAVM
SQ PGGAHGPPPGYGCAAAGYLDGRLEPLYERVGAPALRPLVIKQEPREEDEAKQLALAGLFP
SQ YQPPPPPPPSHPHPHPPPAHLAAPHLQFQIAHCGQTTMHLQPGHPTPPPTPVPSPHPAPA
SQ LGAAGLPGPGSALKGLGAAHPDLRASGGTGAGKAKKSVDKNSNEYRVRRERNNIAVRKSR
SQ DKAKQRNVETQQKVLELTSDNDRLRKRVEQLSRELDTLRGIFRQLPESSLVKAMGNCA
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SC Swiss-Prot#P49715
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FT 280 344 SM00338; brlzneu.
FT 281 334 PF07716; Basic region leucine zipper.
FT 282 345 PS50217; BZIP.
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IN T01067 AML1; human, Homo sapiens.
IN T09104 FOXO1A; mouse, Mus musculus.
IN T09383 GABP-alpha; human, Homo sapiens.
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MX M00116 V$CEBPA_01.
MX M07037 V$CEBPA_Q4.
MX M01866 V$CEBPA_Q6.
MX M00159 V$CEBP_01.
MX M00201 V$CEBP_C.
MX M00190 V$CEBP_Q2.
MX M00912 V$CEBP_Q2_01.
MX M00770 V$CEBP_Q3.
MX M00249 V$CHOP_01.
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BS R00207.
BS R02132.
BS R00631.
BS R00632.
BS R00637.
BS R23169.
BS R23171.
BS R23172.
BS R23174.
BS R23175.
BS R23176.
BS R23177.
BS R23178.
BS R04505.
BS R34699.
BS R00239.
BS R65218.
BS R66516.
BS R60555.
BS R29485.
BS R19930.
BS R19931.
BS R14609.
BS R31180.
BS R35631.
BS R60556.
BS R60557.
BS R42260.
BS R42264.
BS R60554.
BS R00125.
BS R00127.
BS R23166.
BS R23168.
BS R64700.
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DR TRANSPATH: MO000058351.
DR EMBL: U34070;
DR UniProtKB: P49715;
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RN [1]; RE0025710.
RX PUBMED: 11867521.
RA Wang H., Goode T., Iakova P., Albrecht J. H., Timchenko N. A.
RT C/EBPalpha triggers proteasome-dependent degradation of cdk4 during growth arrest.
RL EMBO J. 21:930-41 (2002).
RN [2]; RE0032033.
RX PUBMED: 12757710.
RA Iakova P., Awad S. S., Timchenko N. A.
RT Aging reduces proliferative capacities of liver by switching pathways of C/EBPalpha growth arrest.
RL Cell 113:495-506 (2003).
RN [3]; RE0048580.
RX PUBMED: 15928042.
RA Shimokawa T., Ra C.
RT C/EBPalpha functionally and physically interacts with GABP to activate the human myeloid IgA Fc receptor (Fc alphaR, CD89) gene promoter.
RL Blood 106:2534-2542 (2005).
RN [4]; RE0055446.
RX PUBMED: 17540774.
RA Pham T. H., Langmann S., Schwarzfischer L., El Chartouni C., Lichtinger M., Klug M., Krause S. W., Rehli M.
RT CCAAT enhancer-binding protein beta regulates constitutive gene expression during late stages of monocyte to macrophage differentiation.
RL J. Biol. Chem. 282:21924-21933 (2007).
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