AC T09092
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ID T09092
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DT 16.06.2006 (created); ran.
DT 17.08.2006 (updated); sri.
CO Copyright (C), QIAGEN.
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FA PC4
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SY p14; p15; PC4; positive cofactor 4.
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G006537 SUB1; HGNC: SUB1.
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SZ 127 AA; 14.4 kDa (cDNA) (calc.), 19 kDa (SDS) [3]
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SQ MPKSKELVSSSSSGSDSDSEVDKKLKRKKQVAPEKPVKKQKTGETSRALSSSKQSSSSRD
SQ DNMFQIGKMRYVSVRDFKGKVLIDIREYWMDPEGEMKPGRKGISLNPEQWSQLKEQISDI
SQ DDAVRKL
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SC Swiss-Prot#P53999
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FT 34 124 
PF02229; Transcriptional Coactivator p15 (PC4).
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IN T01042 HSF1-L; human, Homo sapiens.
IN T09196 HSF2A; human, Homo sapiens.
IN T08321 p53-isoform1; human, Homo sapiens.
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DR TRANSPATH: MO000083138.
DR EMBL: U12979;
DR EMBL: X79805;
DR UniProtKB: P53999;
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RN [1]; RE0005547.
RX PUBMED: 1889091.
RA Meisterernst M., Roy A. L., Lieu H. M., Roeder R. G.
RT Activation of class II gene transcription by regulatory factors is potentiated by a novel activity
RL Cell 66:981-993 (1991).
RN [2]; RE0005616.
RX PUBMED: 7809103.
RA Ge H., Zhao Y., Chait B. T., Roeder R. G.
RT Phosphorylation negatively regulates the function of coactivator PC4
RL Proc. Natl. Acad. Sci. USA 91:12691-12695 (1994).
RN [3]; RE0005617.
RX PUBMED: 8062391.
RA Ge H., Roeder R. G.
RT Purification, cloning, and characterization of a human coactivator, PC4, that mediates transcriptional activation of class II genes
RL Cell 78:513-523 (1994).
RN [4]; RE0005619.
RX PUBMED: 8062392.
RA Kretzschmar M., Kaiser K., Lottspeich F., Meisterernst M.
RT A novel mediator of class I gene transcription with homology to viral immediate-early transcriptional regulators
RL Cell 78:525-534 (1994).
RN [5]; RE0005621.
RX PUBMED: 7628453.
RA Kaiser K., Stelzer G., Meisterernst M.
RT The coactivator p15 (PC4) initiates transcriptional activation during TFIIA-TFIID-promoter complex formation
RL EMBO J. 14:3520-3527 (1995).
RN [6]; RE0031850.
RX PUBMED: 11005381.
RA Yuan C. X., Gurley W. B.
RT Potential targets for HSF1 within the preinitiation complex.
RL Cell Stress Chaperones 5:229-42 (2000).
RN [7]; RE0047883.
RX PUBMED: 14966284.
RA Banerjee S., Kumar B. R., Kundu T. K.
RT General transcriptional coactivator PC4 activates p53 function.
RL Mol. Cell. Biol. 24:2052-2062 (2004).
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