AC T09129
XX
ID T09129
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DT 27.07.2006 (created); rad.
DT 22.10.2012 (updated); prb.
CO Copyright (C), QIAGEN.
XX
FA BCL-6-isoform1
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SY B cell lymphoma 6 protein; BCL-5; BCL-6; LAZ-3; Zinc finger and BTB domain-containing protein 27; zinc finger protein 51; ZNF51.
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G004696 BCL6; HGNC: BCL6.
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CL C0058; CH+BTB/POZ.
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SZ 706 AA; 78.8 kDa (cDNA) (calc.), 95 kDa (SDS) [3]
XX
SQ MASPADSCIQFTRHASDVLLNLNRLRSRDILTDVVIVVSREQFRAHKTVLMACSGLFYSI
SQ FTDQLKCNLSVINLDPEINPEGFCILLDFMYTSRLNLREGNIMAVMATAMYLQMEHVVDT
SQ CRKFIKASEAEMVSAIKPPREEFLNSRMLMPQDIMAYRGREVVENNLPLRSAPGCESRAF
SQ APSLYSGLSTPPASYSMYSHLPVSSLLFSDEEFRDVRMPVANPFPKERALPCDSARPVPG
SQ EYSRPTLEVSPNVCHSNIYSPKETIPEEARSDMHYSVAEGLKPAAPSARNAPYFPCDKAS
SQ KEEERPSSEDEIALHFEPPNAPLNRKGLVSPQSPQKSDCQPNSPTESCSSKNACILQASG
SQ SPPAKSPTDPKACNWKKYKFIVLNSLNQNAKPEGPEQAELGRLSPRAYTAPPACQPPMEP
SQ ENLDLQSPTKLSASGEDSTIPQASRLNNIVNRSMTGSPRSSSESHSPLYMHPPKCTSCGS
SQ QSPQHAEMCLHTAGPTFPEEMGETQSEYSDSSCENGAFFCNECDCRFSEEASLKRHTLQT
SQ HSDKPYKCDRCQASFRYKGNLASHKTVHTGEKPYRCNICGAQFNRPANLKTHTRIHSGEK
SQ PYKCETCGARFVQVAHLRAHVLIHTGEKPYPCEICGTRFRHLQTLKSHLRIHTGEKPYHC
SQ EKCNLHFRHKSQLRLHLRQKHGAITNTKVQYRVSATDLPPELPKAC
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SC Swiss-Prot#P41182
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FT 22 129 
PF00651; BTB/POZ domain.
FT 32 99 
PS50097; BTB.
FT 32 129 
SM00225; BTB_4.
FT 66 630 
PF00478; IMP dehydrogenase / GMP reductase domain.
FT 518 541 
PF00096; zf-C2H2.
FT 518 541 
SM00355; c2h2final6.
FT 518 546 
PS50157; ZINC_FINGER_C2H2_2.
FT 546 568 
PF00096; zf-C2H2.
FT 546 568 
SM00355; c2h2final6.
FT 546 573 
PS50157; ZINC_FINGER_C2H2_2.
FT 574 596 PF00096; zf-C2H2.
FT 574 596 SM00355; c2h2final6.
FT 574 601 PS50157; ZINC_FINGER_C2H2_2.
FT 602 624 PF00096; zf-C2H2.
FT 602 624 SM00355; c2h2final6.
FT 602 629 PS50157; ZINC_FINGER_C2H2_2.
FT 630 652 PF00096; zf-C2H2.
FT 630 652 SM00355; c2h2final6.
FT 630 657 PS50157; ZINC_FINGER_C2H2_2.
FT 658 681 PF00096; zf-C2H2.
FT 658 681 PS50157; ZINC_FINGER_C2H2_2.
FT 658 681 SM00355; c2h2final6.
XX
IN T34300 BCOR-isoform2; human, Homo sapiens.
IN T34301 BCOR-S; human, Homo sapiens.
IN T34274 BCOR; human, Homo sapiens.
IN T04687 NCOR1; human, Homo sapiens.
IN T23741 PATZ-isoform4; human, Homo sapiens.
IN T04689 SMRT; human, Homo sapiens.
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MX M01183 V$BCL6_01.
MX M01185 V$BCL6_02.
MX M01171 V$BCL6_Q3.
MX M02085 V$BCL6_Q3_01.
MX M07375 V$BCL6_Q6.
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BS R04643.
BS R23968.
BS R23969.
BS R23970.
BS R23971.
BS R23972.
BS R23973.
BS R23974.
BS R23975.
BS R23976.
BS R23977.
BS R23978.
BS R23979.
BS R23980.
BS R23981.
BS R23982.
BS R23983.
BS R23984.
BS R23985.
BS R23986.
BS R23987.
BS R23988.
BS R23989.
BS R23990.
BS R23991.
BS R23992.
BS R23993.
BS R23994.
BS R23995.
BS R23996.
BS R23997.
BS R23998.
BS R23999.
BS R00702.
BS R13024.
BS R13025.
BS R13026.
BS R36627.
BS R36487.
BS R36623.
XX
DR TRANSPATH: MO000083699.
DR EMBL: U00115;
DR UniProtKB: P41182;
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RN [1]; RE0006494.
RX PUBMED: 8235596.
RA Ye B. H., Lista F., Lo Coco F., Knowles D. M., Offit K., Chaganti R. S. K., Dalla-Favera R.
RT Alterations of a zinc finger-encoding gene BCL-6, in diffuse large-cell lymphoma
RL Science 262:747-750 (1993).
RN [2]; RE0006495.
RX PUBMED: 9135990.
RA Baron B. W., Desai M., Baber L. J., Paras L., Zhang Q., Sadhu A., Duguay S., Nucifora G., McKeithan T. W., Zeleznik-Le N.
RT BCL6 can repress transsription from the human immunodeficiency virus typeI promoter/enhancer region
RL Genes Chromosomes Cancer 19:14-21 (1997).
RN [3]; RE0006496.
RX PUBMED: 8692924.
RA Chang C.-C., Ye B. H., Chaganti R. S. K., Dalla-Favera R.
RT BCL-6, a POZ/zinc-finger protein, is a sequence-specific transcriptional repressor
RL Proc. Natl. Acad. Sci. USA 93:6947-6952 (1996).
RN [4]; RE0026599.
RX PUBMED: 10898795.
RA Huynh K. D., Fischle W., Verdin E., Bardwell V. J.
RT BCoR, a novel corepressor involved in BCL-6 repression.
RL Genes Dev. 14:1810-23 (2000).
RN [5]; RE0047935.
RX PUBMED: 9765306.
RA Wong C. W., Privalsky M. L.
RT Components of the SMRT corepressor complex exhibit distinctive interactions with the POZ domain oncoproteins PLZF, PLZF-RARalpha, and BCL-6.
RL J. Biol. Chem. 273:27695-27702 (1998).
RN [6]; RE0052481.
RX PUBMED: 12590135.
RA Petrie K., Guidez F., Howell L., Healy L., Waxman S., Greaves M., Zelent A.
RT The histone deacetylase 9 gene encodes multiple protein isoforms.
RL J. Biol. Chem. 278:16059-16072 (2003).
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