AC T09284
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ID T09284
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DT 31.08.2006 (created); man.
DT 02.11.2006 (updated); ech.
CO Copyright (C), QIAGEN.
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FA RORalpha
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SY NR1F1; RAR-related orphan receptor alpha; ROR1; ROR2; ROR3; RORA; sg; staggerer.
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OS mouse, Mus musculus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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GE G009894 Rora.
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CL C0002; CC (rec); 2.1.2.6.1.1.
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SZ 523 AA; 58.8 kDa (cDNA) (calc.).
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SQ MESAPAAPDPAASEPGSSGSEAAAGSRETPLTQDTGRKSEAPGAGRRQSYASSSRGISVT
SQ KKTHTSQIEIIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRT
SQ SRNRCQHCRLQKCLAVGMSRDAVKFGRMSKKQRDSLYAEVQKHRMQQQQRDHQQQPGEAE
SQ PLTPTYNISANGLTELHDDLSTYMDGHTPEGSKADSAVSSFYLDIQPSPDQSGLDINGIK
SQ PEPICDYTPASGFFPYCSFTNGETSPTVSMAELEHLAQNISKSHLETCQYLREELQQITW
SQ QTFLQEEIENYQNKQREVMWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGS
SQ LEVVFIRMCRAFDSQNNTVYFDGKYASPDVFKSLGCEDFISFVFEFGKSLCSMHLTEDEI
SQ ALFSAFVLMSADRSWLQEKVKIEKLQQKIQLALQHVLQKNHREDGILTKLICKVSTLRAL
SQ CGRHTEKLMAFKAIYPDIVRLHFPPLYKELFTSEFEPAMQIDG
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SC translated from EMBL #U53228
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FT 70 141 
SM00399; c4gold.
FT 70 145 
PS51030; NUCLEAR_REC_DBD_2.
FT 71 146 
PF00105; Zinc finger, C4 type (two domains).
FT 105 461 
PF00478; IMP dehydrogenase / GMP reductase domai.
FT 325 481 
SM00430; holi.
FT 328 510 
PF00104; Ligand-binding domain of nuclear hormon.
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FF participates in bone metabolism [3];
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IN T10027 MyoD; Mammalia.
IN T01427 p300; human, Homo sapiens.
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MX M00156 V$RORA1_01.
MX M00157 V$RORA2_01.
MX M07306 V$RORALPHA_Q4.
MX M01138 V$RORA_Q4.
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DR TRANSPATH: MO000086055.
DR EMBL: U53228;
DR UniProtKB: P51448-1;
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RN [1]; RE0024667.
RX PUBMED: 12150932.
RA Preitner N., Damiola F., Lopez-Molina L., Zakany J., Duboule D., Albrecht U., Schibler U.
RT The orphan nuclear receptor REV-ERBalpha controls circadian transcription within the positive limb of the mammalian circadian oscillator.
RL Cell 110:251-260 (2002).
RN [2]; RE0048173.
RX PUBMED: 9862959.
RA Lau P., Bailey P., Dowhan D. H., Muscat G. E.
RT Exogenous expression of a dominant negative RORalpha1 vector in muscle cells impairs differentiation: RORalpha1 directly interacts with p300 and myoD.
RL Nucleic Acids Res. 27:411-420 (1999).
RN [3]; RE0048613.
RX PUBMED: 10900268.
RA Meyer T., Kneissel M., Mariani J., Fournier B.
RT In vitro and in vivo evidence for orphan nuclear receptor RORalpha function in bone metabolism.
RL Proc. Natl. Acad. Sci. USA 97:9197-9202 (2000).
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//