AC T09288
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ID T09288
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DT 04.09.2006 (created); man.
DT 04.09.2006 (updated); man.
CO Copyright (C), QIAGEN.
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FA Pontin52-isoform1
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SY 49 kDa TBP-interacting protein; 49-kDa TATA box-binding protein-interacting protein; 54 kDa erythrocyte cytosolic protein; ECP-54; NMP238; nuclear matrix protein 238; RuvB-like 1; RUVBL1; TAP54-alpha; TIP49; TIP49a; TIP60-associated protein 54-alpha.
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G009948 RUVBL1; HGNC: RUVBL1.
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SZ 456 AA; 50.2 kDa (cDNA) (calc.), 52 kDa (SDS) [1]
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SQ MKIEEVKSTTKTQRIASHSHVKGLGLDESGLAKQAASGLVGQENAREACGVIVELIKSKK
SQ MAGRAVLLAGPPGTGKTALALAIAQELGSKVPFCPMVGSEVYSTEIKKTEVLMENFRRAI
SQ GLRIKETKEVYEGEVTELTPCETENPMGGYGKTISHVIIGLKTAKGTKQLKLDPSIFESL
SQ QKERVEAGDVIYIEANSGAVKRQGRCDTYATEFDLEAEEYVPLPKGDVHKKKEIIQDVTL
SQ HDLDVANARPQGGQDILSMMGQLMKPKKTEITDKLRGEINKVVNKYIDQGIAELVPGVLF
SQ VDEVHMLDIECFTYLHRALESSIAPIVIFASNRGNCVIRGTEDITSPHGIPLDLLDRVMI
SQ IRTMLYTPQEMKQIIKIRAQTEGINISEEALNHLGEIGTKTTLRYSVQLLTPANLLAKIN
SQ GKDSIEKEHVEEISELFYDAKSSAKILADQQDKYMK
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SC translated from EMBL #AF099084
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FT 22 348 
PF00478; IMP dehydrogenase / GMP reductase domain.
FT 62 365 
SM00382; AAA_5.
FT 70 77 
Walker A motif (ATP/ GTP binding) [1].
FT 117 440 
PF06068; TIP49 C-terminus.
FT 302 305 
Walker B motif (ATP/ GTP binding) [1].
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IN T14435 c-Myc; Mammalia.
IN T03214 Pontin52; human, Homo sapiens.
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DR TRANSPATH: MO000086195.
DR EMBL: AF099084; AF099084.
DR UniProtKB: Q9Y265;
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RN [1]; RE0014262.
RX PUBMED: 9843967.
RA Bauer A., Huber O., Kemler R.
RT Pontin52, an interaction partner of beta-catenin, binds to the TATA box binding protein
RL Proc. Natl. Acad. Sci. USA 95:14787-14792 (1998).
RN [2]; RE0020778.
RX PUBMED: 11080158.
RA Bauer A., Chauvet S., Huber O., Usseglio F., Rothbacher U., Aragnol D., Kemler R., Pradel J.
RT Pontin52 and reptin52 function as antagonistic regulators of beta-catenin signalling activity
RL EMBO J. 19:6121-6130 (2000).
RN [3]; RE0027531.
RX PUBMED: 10882073.
RA Wood M. A., McMahon S. B., Cole M. D.
RT An ATPase/helicase complex is an essential cofactor for oncogenic transformation by c-Myc.
RL Mol. Cell 5:321-30 (2000).
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