AC T09291
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ID T09291
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DT 04.09.2006 (created); lyn.
DT 16.11.2006 (updated); mkl.
CO Copyright (C), QIAGEN.
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FA HOXD13
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SY Hox-4.8; Hoxd-13.
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OS mouse, Mus musculus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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GE G006235 Hoxd13.
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CL C0006; homeo.
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SZ 339 AA; 35.9 kDa (cDNA) (calc.).
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SQ MSRSGTWDMDGLRADGGAAGAAPASSSSSVAAPGQCRGFLSAPVFAGTHSGRAAAAAAAA
SQ AAAAAAASTFAYPGTSERTGSSSSSSSSAVIATRPEAPVAKECPAPAAAATAAAPPGAPA
SQ LGYGYHFGNGYYSCRMSHGVGLQQNALKSSPHASLGGFPVEKYMDVSGLASSSVPTNEVP
SQ ARAKEVSFYQGYTSPYQHVPGYIDMVSTFGSGEPRHEAYISMEGYQSWTLANGWNSQVYC
SQ AKDQPQGSHFWKSSFPGDVALNQPDMCVYRRGRKKRVPYTKLQLKELENEYAINKFINKD
SQ KRRRISAATNLSERQVTIWFQNRRVKDKKIVSKLKDTVS
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SC translated from EMBL #X99291
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FT 270 330 
PS50071; HOMEOBOX_2.
FT 272 334 
SM00389; HOX_1.
FT 273 329 
PF00046; Homeobox domain.
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IN T08914 Smad1; mouse, Mus musculus.
IN T09086 Smad2; mouse, Mus musculus.
IN T08915 Smad5; mouse, Mus musculus.
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MX M07456 V$HOXA913_Q4.
MX M01404 V$HOXD13_01.
MX M08817 V$HOXD13_Q6.
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BS R18690.
BS R18689.
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DR TRANSPATH: MO000086210.
DR EMBL: S80553;
DR EMBL: X99291;
DR UniProtKB: P70217;
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RN [1]; RE0004078.
RX PUBMED: 1685889.
RA Dolle P., Izpisua-Belmonte J. C., Boncinelli E., Duboule D.
RT The Hox-4.8 gene is localized at the 5' extremity of the Hox-4 complex and is expressed in the most posterior parts of the body during development
RL Mech. Dev. 36:3-13 (1991).
RN [2]; RE0004079.
RX PUBMED: 8106170.
RA Dolle P., Dierich A., LeMeur M., Schimmang T., Schuhbaur B., Chambon P., Duboule D.
RT Disruption of the Hoxd-13 gene induces localized heterochrony leading to mice with neotenic limbs
RL Cell 75:431-441 (1993).
RN [3]; RE0013481.
RX PUBMED: 8978698.
RA Herault Y., Hraba-Renevey S., van der Hoeven F., Duboule D.
RT Function of the Evx-2 gene in the morphogenesis of vertebrate limbs
RL EMBO J. 15:6727-6738 (1996).
RN [4]; RE0048182.
RX PUBMED: 16087734.
RA Williams T. M., Williams M. E., Heaton J. H., Gelehrter T. D., Innis J. W.
RT Group 13 HOX proteins interact with the MH2 domain of R-Smads and modulate Smad transcriptional activation functions independent of HOX DNA-binding capability.
RL Nucleic Acids Res. 33:4475-4484 (2005).
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