AC T09905
XX
ID T09905
XX
DT 12.11.2006 (created); sou.
DT 28.07.2014 (updated); pos.
CO Copyright (C), QIAGEN.
XX
FA B-Myb
XX
SY B-Myb; BMYB; MYBL2.
XX
OS mouse, Mus musculus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
XX
GE G001215 Mybl2.
XX
CL C0022; trp.
XX
SZ 704 AA; 79.1 kDa (cDNA) (calc.).
XX
SQ MSRRTRCEDLDELHYQDVDSDLLEQRDNRCKVKWTHEEDEQLRALVRQFGQQDWKFLASH
SQ FPNRTDQQCQYRWLRVLNPDLVKGPWTKEEDQKVIELVKKYGTKQWTLIAKHLKGRLGKQ
SQ CRERWHNHLNPEVKKSCWTEEEDRIICEAHKVLGNRWAEIAKMLPGRTDNAVKNHWNSTI
SQ KRKVDTGGFPAESRDCKPVYLLLELEDKEQHQGVQPVDGQGSLVSSWPLVPSIVKEESSE
SQ EEIAIAATSAKELGHEPVPADLGEVRTPEPPESLKREYQEFSSPETSLPYKWVVEAANLL
SQ IPAVGSSLSEALDLIESDPDAWCDLSKFDLPEEPSTEGSVVSSPVQPQTSQQQQEEALQS
SQ SQQAATPGPSVTEYRLDGHTISDLSRSSRGELIPISPSTEFGGSGIGTPPSVLKRQKKRR
SQ VALSPVTENSASLSFLDSCNSLTPKSTPVKTLPFSPSQFLNFWNKQDTLELESPSLTSTP
SQ VCSQKVVVTTPLHRDKTPLHQKYPSSEVLPDQKYSMDNTPHTPTPFKNALEKYGPLKPLP
SQ QTPHLEEDLKEVLRSEAGMELIIEDDMRPEKQKRKPGLRRSPIKKVRKSLALDIMDEDGK
SQ LMSSTMPKPLSLPTSVTPSSCGFTSPGSKEGNSLLNQGFLQAKPEKVVAAQKTRSHIPTP
SQ APMTHAWKTVACGGTKDQLFMQEKARQLLSRLKSSHTSRTLILS
XX
SC translated from EMBL #X73028
XX
FT 26 77 
PS50090; MYB_3.
FT 30 79 
SM00717; sant.
FT 31 77 
PF00249; Myb-like DNA-binding domain.
FT 78 129 
PS50090; MYB_3.
FT 82 131 
SM00717; sant.
FT 83 129 
PF00249; Myb-like DNA-binding domain.
FT 130 180 
PS50090; MYB_3.
FT 134 182 
SM00717; sant.
FT 135 180 
PF00249; Myb-like DNA-binding domain.
FT 192 698 
PF00478; IMP dehydrogenase / GMP reductase dom.
XX
IN T15118 CBP; Mammalia.
IN T08641 NCOR1-isoform1; mouse, Mus musculus.
IN T01427 p300; human, Homo sapiens.
IN T09272 SMRT-Alpha; mouse, Mus musculus.
XX
MX M00913 V$MYB_Q5_01.
MX M08890 V$MYB_Q5_02.
XX
BS R13158.
XX
DR TRANSPATH: MO000092031.
DR EMBL: X70472;
DR EMBL: X73028;
DR UniProtKB: P48972;
XX
RN [1]; RE0003295.
RX PUBMED: 8334989.
RA Lam E. W.-F., Watson R. J.
RT An E2F-binding site mediates cell-cycle regulated repression of mouse B-myb transcription
RL EMBO J. 12:2705-2713 (1993).
RN [2]; RE0003583.
RX PUBMED: 1501895.
RA Lam E. W., Robinson C., Watson R. J.
RT Characterization and cell cycle-regulated expression of mouse B-myb
RL Oncogene 7:1885-1890 (1992).
RN [3]; RE0003585.
RX PUBMED: 8382794.
RA Watson R. J., Robinson C., Lam E. W.
RT Transcription regulation by murine B-myb is distinct from that by c-myb
RL Nucleic Acids Res. 21:267-272 (1993).
RN [4]; RE0046322.
RX PUBMED: 11997503.
RA Li X., McDonnell D. P.
RT The transcription factor B-Myb is maintained in an inhibited state in target cells through its interaction with the nuclear corepressors N-CoR and SMRT
RL Mol. Cell. Biol. 22:3663-73 (2002).
RN [5]; RE0048800.
RX PUBMED: 11485831.
RA Masselink H., Vastenhouw N., Bernards R.
RT B-myb rescues ras-induced premature senescence, which requires its transactivation domain.
RL Cancer Lett. 171:87-101 (2001).
XX
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