AC T10214
XX
ID T10214
XX
DT 02.02.2007 (created); pra.
DT 15.11.2011 (updated); mkl.
CO Copyright (C), QIAGEN.
XX
FA GABP-alpha
XX
SY GA binding protein alpha subunit; GABP-alpha; NRF-2alpha.
XX
OS mouse, Mus musculus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
XX
GE G004133 Gabpa.
XX
CL C0016; ETS.
XX
SZ 454 AA; 51.4 kDa (cDNA) (calc.), 66 kDa (GF, sedim.)
XX
SQ MTKREAEELIEIEIDGTEKAECTEESIVEQTYTPAECVSQAIDINEPIGNLKKLLEPRLQ
SQ CSLDAHEICLQDIQLDPDRSLFDQGVKTDGTVQLSVQVISYQGMEPKLNILEIVKTAETV
SQ EVVIDPDAHHAEAEAHLVEEAQVITLDGTKHITTISDETSEQVTRWAAALEGYRKEQERL
SQ GIPYDPIRWSTDQVLHWVVWVMKEFSMTDIDLTTLNISGRELCSLNQEDFFQRVPRGEIL
SQ WSHLELLRKYVLASQEQQMNEIVTIDQPVQIIPASVPPATPTTIKVINSSAKAAKVQRSP
SQ RISGEDRSSPGNRTGNNGQIQLWQFLLELLTDKDARDCISWVGDEGEFKLNQPELVAQKW
SQ GQRKNKPTMNYEKLSRALRYYYDGDMICKVQGKRFVYKFVCDLKTLIGYSAAELNRLVIE
SQ CEQKKLARMQLHGIAQPVTAVALAATSLQADKEI
XX
SC Swiss-Prot#Q00422
XX
FT 66 439 
PF00478; IMP dehydrogenase / GMP reductase domain.
FT 170 251 
PF02198; Sterile alpha motif (SAM)/Pointed domain.
FT 170 251 
SM00251; SAM2_3.
FT 185 249 
POINTED domain of homology [3].
FT 319 402 
PF00178; Ets-domain.
FT 319 404 
SM00413; etsneu2.
FT 320 400 
PS50061; ETS_DOMAIN_3.
FT 322 390 
PS50140; HSF_ETS.
FT 401 437 
auxiliary for interaction with GABP-beta [2].
XX
IN T08326 Sp1; Mammalia.
IN T08327 Sp3; Mammalia.
XX
MX M08881 V$ETSLIKE_Q4.
MX M00971 V$ETS_Q6.
MX M01660 V$GABPA_Q4.
MX M00341 V$GABP_B.
XX
BS R21799.
BS R14800.
BS R20444.
BS R20411.
BS R26932.
XX
DR TRANSPATH: MO000098126.
DR EMBL: M74515;
DR UniProtKB: Q00422;
XX
RN [1]; RE0002667.
RX PUBMED: 1876836.
RA LaMarco K., Thompson C. C., Byers B. P., Walton E. M., McKnight S. L.
RT Identification of Ets- and Notch-related subunits in GA binding proteins
RL Science 253:789-792 (1991).
RN [2]; RE0002668.
RX PUBMED: 1876833.
RA Thompson C. C., Brown T. A., McKnight S. L.
RT Convergence of Ets- and Notch-related structural motifs in a heteromeric DNA binding complex
RL Science 253:762-768 (1991).
RN [3]; RE0005316.
RX PUBMED: 8223245.
RA Klaembt C.
RT The Drosophila gene pointed encodes two ETS-like proteins which are involved in the development of the midline glial cells
RL Development 117:163-176 (1993).
XX
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