AC T11136
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ID T11136
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DT 15.11.2007 (created); bch.
DT 22.01.2013 (updated); spk.
CO Copyright (C), QIAGEN.
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FA DEC2
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SY basic helix-loop-helix domain containing, class B3; Bhlhb2l; Bhlhb3; dec2; Differentially expressed in chondrocytes protein 2; mDEC2; Sharp1.
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OS mouse, Mus musculus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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GE G009153 Bhlhe41.
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CL C0010; bHLH.
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SZ 410 AA; 43.9 kDa (calc.).
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SQ MDEGIPHLQERQLLEHRDFIGLDYSSLYMCKPKRSLKRDDTKDTYKLPHRLIEKKRRDRI
SQ NECIAQLKDLLPEHLKLTTLGHLEKAVVLELTLKHLKALTALTEQQHQKIIALQNGERSL
SQ KSPVQADLDAFHSGFQTCAKEVLQYLARFESWTPREPRCAQLVSHLHAVATQLLTPQVPS
SQ GRGSGRAPCSAGAAAASGPERVARCVPVIQRTQPGTEPEHDTDTDSGYGGEAEQGRAAVK
SQ QEPPGDSSPAPKRPKLEARGALLGPEPALLGSLVALGGGAPFAQPAAAPFCLPFYLLSPS
SQ AAAYVQPWLDKSGLDKYLYPAAAAPFPLLYPGIPAAAAAAAAAAFPCLSSVLSPPPEKAG
SQ ATAGAPFLAHEVAPPGPLRPQHAHSRTHLPRAVNPESSQEDATQPAKDAP
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SC translated from EMBL #AB044090
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FT 20 367 
PF00478; IMP dehydrogenase / GMP reductase domain.
FT 37 100 
PS50888; HLH.
FT 43 100 
bHLH domain [2].
FT 45 100 
PF00010; Helix-loop-helix DNA-binding domain.
FT 50 105 
SM00353; finulus.
FT 129 175 
PF07527; Hairy Orange.
FT 129 175 
SM00511; ORANGE.
FT 130 173 
orange domain [2].
FT 131 166 
PS51054; ORANGE.
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IN T01610 HIF-1alpha; human, Homo sapiens.
IN T10851 HIF2A; human, Homo sapiens.
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MX M01843 V$DEC2_Q2.
MX M08871 V$DEC2_Q3.
MX M00997 V$DEC_Q1.
MX M08872 V$DEC_Q3.
MX M01034 V$EBOX_Q6_01.
MX M08885 V$HAIRYLIKE_Q3.
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BS R14564.
BS R32773.
BS R14561.
BS R14562.
BS R14563.
BS R32737.
BS R32739.
BS R14604.
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DR TRANSPATH: MO000117588.
DR EMBL: AB044090;
DR UniProtKB: Q99PV5;
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RN [1]; RE0023788.
RX PUBMED: 11162494.
RA Fujimoto K., Shen M., Noshiro M., Matsubara K., Shingu S., Honda K., Yoshida E., Suardita K., Matsuda Y., Kato Y.
RT Molecular cloning and characterization of DEC2, a new member of basic helix-loop-helix proteins.
RL Biochem. Biophys. Res. Commun. 280:164-171 (2001).
RN [2]; RE0023854.
RX PUBMED: 12657651.
RA Azmi S., Sun H., Ozog A., Taneja R.
RT mSharp-1/DEC2, a basic helix-loop-helix protein functions as a transcriptional repressor of E box activity and Stra13 expression.
RL J. Biol. Chem. 278:20098-20109 (2003).
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//