AC T14280
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ID T14280
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DT 20.09.2006 (created); ran.
DT 28.08.2015 (updated); jtr.
CO Copyright (C), QIAGEN.
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FA Ku70:Ku80
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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CP breast cancer tissue [1].
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IN T34781 ErbB1; human, Homo sapiens.
IN T10036 HSF1; human, Homo sapiens.
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BS R23856.
BS R36500.
BS R69455.
BS R28301.
BS R58993.
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DR TRANSPATH: MO000087568.
DR TRANSCOMPEL: C00549.
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RN [1]; RE0027611.
RX PUBMED: 11314007.
RA Pucci S., Mazzarelli P., Rabitti C., Giai M., Gallucci M., Flammia G., Alcini A., Altomare V., Fazio V. M.
RT Tumor specific modulation of KU70/80 DNA binding activity in breast and bladder human tumor biopsies.
RL Oncogene 20:739-47 (2001).
RN [2]; RE0029337.
RX PUBMED: 9430697.
RA Bandyopadhyay D., Mandal M., Adam L., Mendelsohn J., Kumar R.
RT Physical interaction between epidermal growth factor receptor and DNA-dependent protein kinase in mammalian cells.
RL J. Biol. Chem. 273:1568-73 (1998).
RN [3]; RE0048301.
RX PUBMED: 15023334.
RA Cohen H. Y., Lavu S., Bitterman K. J., Hekking B., Imahiyerobo T. A., Miller C., Frye R., Ploegh H., Kessler B. M., Sinclair D. A.
RT Acetylation of the C terminus of Ku70 by CBP and PCAF controls Bax-mediated apoptosis.
RL Mol. Cell 13:627-638 (2004).
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