AC T10036
XX
ID T10036
XX
DT 25.10.2002 (created); cch.
DT 15.04.2016 (updated); sup.
CO Copyright (C), QIAGEN.
XX
FA HSF1
XX
SY heat shock factor 1.
XX
OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
XX
GE G004875 HSF1; HGNC: HSF1.
XX
CL C0050; HSF; 3.4.1.0.1.
XX
IN T05778 ASC-2; human, Homo sapiens.
IN T01043 HSF2; human, Homo sapiens.
IN T08835 Ku70-isoform1; human, Homo sapiens.
IN T14280 Ku70:Ku80; human, Homo sapiens.
IN T04759 STAT1; human, Homo sapiens.
IN T02113 TAFII31; human, Homo sapiens.
XX
MX M00146 V$HSF1_01.
MX M04008 V$HSF1_02.
MX M04761 V$HSF1_03.
MX M07100 V$HSF1_04.
MX M07259 V$HSF1_Q5.
MX M07459 V$HSF1_Q5_01.
MX M01023 V$HSF1_Q6.
MX M02017 V$HSF1_Q6_01.
MX M00641 V$HSF_Q6.
XX
BS R24198.
BS R24199.
BS R24200.
BS R09927.
BS R62006.
BS R37613.
BS R37614.
BS R34173.
BS R27284.
BS R68902.
BS R68908.
BS R68910.
BS R68912.
BS R68917.
BS R68919.
BS R68920.
BS R68921.
BS R36632.
BS R36633.
BS R65902.
BS R65906.
BS R65907.
BS R36856.
BS R63096.
BS R63097.
BS R22111.
BS R37551.
BS R00762.
BS R00763.
BS R00764.
BS R33022.
BS R37552.
BS R40028.
BS R37341.
BS R62733.
BS R62745.
BS R71659.
BS R65580.
BS R64279.
BS R65643.
BS R72355.
BS R72357.
BS R40029.
BS R40031.
BS R64659.
BS R60941.
BS R20950.
BS R66320.
BS R72797.
BS R63596.
BS R36895.
BS R72394.
BS R37184.
BS R37978.
BS R65908.
BS R65910.
BS R36849.
BS R71652.
BS R66304.
BS R33808.
BS R34299.
BS R34308.
BS R37339.
BS R64749.
BS R68284.
BS R65817.
BS R65820.
BS R72400.
BS R69528.
BS R69540.
BS R69541.
BS R65578.
BS R40043.
BS R59743.
BS R59749.
BS R65577.
BS R65575.
BS R23120.
BS R28306.
XX
DR TRANSPATH: MO000033378.
DR UniProtKB: Q00613;
XX
RN [1]; RE0025006.
RX PUBMED: 12813038.
RA He H., Soncin F., Grammatikakis N., Li Y., Siganou A., Gong J., Brown S. A., Kingston R. E., Calderwood S. K.
RT Elevated expression of heat shock factor (HSF) 2A stimulates HSF1-induced transcription during stress.
RL J. Biol. Chem. 278:35465-35475 (2003).
RN [2]; RE0032571.
RX PUBMED: 9880553.
RA Stephanou A., Isenberg D. A., Nakajima K., Latchman D. S.
RT Signal transducer and activator of transcription-1 and heat shock factor-1 interact and activate the transcription of the Hsp-70 and Hsp-90beta gene promoters.
RL J. Biol. Chem. 274:1723-8 (1999).
RN [3]; RE0035810.
RX PUBMED: 9155018.
RA Fukunaga R., Hunter T.
RT MNK1, a new MAP kinase-activated protein kinase, isolated by a novel expression screening method for identifying protein kinase substrates.
RL EMBO J. 16:1921-1933 (1997).
RN [4]; RE0047995.
RX PUBMED: 10821850.
RA Choi Y., Asada S., Uesugi M.
RT Divergent hTAFII31-binding motifs hidden in activation domains.
RL J. Biol. Chem. 275:15912-15916 (2000).
RN [5]; RE0048036.
RX PUBMED: 11162511.
RA Tang D., Xie Y., Zhao M., Stevenson M. A., Calderwood S. K.
RT Repression of the HSP70B promoter by NFIL6, Ku70, and MAPK involves three complementary mechanisms.
RL Biochem. Biophys. Res. Commun. 280:280-285 (2001).
RN [6]; RE0048038.
RX PUBMED: 14707147.
RA Xing H., Mayhew C. N., Cullen K. E., Park-Sarge O. K., Sarge K. D.
RT HSF1 modulation of Hsp70 mRNA polyadenylation via interaction with symplekin.
RL J. Biol. Chem. 279:10551-10555 (2004).
RN [7]; RE0048043.
RX PUBMED: 9499401.
RA Shi Y., Mosser D. D., Morimoto R. I.
RT Molecular chaperones as HSF1-specific transcriptional repressors.
RL Genes Dev. 12:654-666 (1998).
RN [8]; RE0048044.
RX PUBMED: 14960326.
RA Hong S., Kim S. H., Heo M. A., Choi Y. H., Park M. J., Yoo M. A., Kim H. D., Kang H. S., Cheong J.
RT Coactivator ASC-2 mediates heat shock factor 1-mediated transactivation dependent on heat shock.
RL FEBS Lett. 559:165-170 (2004).
RN [9]; RE0048049.
RX PUBMED: 12621024.
RA Hu Y., Mivechi N. F.
RT HSF-1 interacts with Ral-binding protein 1 in a stress-responsive, multiprotein complex with HSP90 in vivo.
RL J. Biol. Chem. 278:17299-17306 (2003).
RN [10]; RE0048789.
RX PUBMED: 12665592.
RA Hietakangas V., Ahlskog J. K., Jakobsson A. M., Hellesuo M., Sahlberg N. M., Holmberg C. I., Mikhailov A., Palvimo J. J., Pirkkala L., Sistonen L.
RT Phosphorylation of serine 303 is a prerequisite for the stress-inducible SUMO modification of heat shock factor 1.
RL Mol. Cell. Biol. 23:2953-2968 (2003).
RN [11]; RE0048834.
RX PUBMED: 15016915.
RA Boellmann F., Guettouche T., Guo Y., Fenna M., Mnayer L., Voellmy R.
RT DAXX interacts with heat shock factor 1 during stress activation and enhances its transcriptional activity.
RL Proc. Natl. Acad. Sci. USA 101:4100-4105 (2004).
RN [12]; RE0052667.
RX PUBMED: 18286539.
RA Franceschelli S., Rosati A., Lerose R., De Nicola S., Turco M. C., Pascale M.
RT Bag3 gene expression is regulated by heat shock factor 1.
RL J. Cell. Physiol. 215:575-577 (2008).
RN [13]; RE0063213.
RX PUBMED: 17897941.
RA Skaggs H. S., Xing H., Wilkerson D. C., Murphy L. A., Hong Y., Mayhew C. N., Sarge K. D.
RT HSF1-TPR interaction facilitates export of stress-induced HSP70 mRNA.
RL J. Biol. Chem. 282:33902-33907 (2007).
XX
//