TRANSFAC FACTOR TABLE, Release 2017.2 - public - 2017-06-30, (C) QIAGEN

AC T02113 XX ID T02113 XX DT 16.05.1997 (created); hiwi. DT 15.05.2014 (updated); ili. CO Copyright (C), QIAGEN. XX FA TAFII31 XX SY AD-004; Adenylate kinase isoenzyme 6; AK6; ATP-AMP transphosphorylase 6; CGI-137; CINAP; Coilin-interacting nuclear ATPase protein; FIX; hCINAP; TAF(II)31; TAF-31; TAF-32; TAF9; TATA box binding protein (TBP)-associated factor, RNA polymerase II, G, 32kD; TBP-associated factor 31; transcription initiation factor TFIID 31 kD subunit. XX OS human, Homo sapiens OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates XX GE G004689 TAF9; HGNC: TAF9. XX HO TAF(II)40 (Drosophila). XX SF calculated pI = 9.8 [3]; XX FF part of TFIID complex [2]; FF co-activator for p53 [3]; FF co-activator for VP16 [1]; FF interacts directly with the acidic activation domain of co-activator CIITA T05450 thus providing expression of MHC class II promoters [6] [7]; XX IN T09193 ALL1-isoform1; human, Homo sapiens. IN T06595 C/EBPbeta-FL; human, Homo sapiens. IN T05450 C2TA; human, Homo sapiens. IN T08505 COUP-TF1; human, Homo sapiens. IN T05449 ESE-1b; human, Homo sapiens. IN T10036 HSF1; human, Homo sapiens. IN T19100 NC2alpha; human, Homo sapiens. IN T19122 NFATc2B; human, Homo sapiens. IN T06148 p/CAF; human, Homo sapiens. IN T00671 p53; human, Homo sapiens. IN T04997 p53; rat, Rattus norvegicus. IN T10397 RelA-p65; Mammalia. IN T16157 TAF2; human, Homo sapiens. IN T00784 TAFII100; human, Homo sapiens. IN T28810 TAFII135; human, Homo sapiens. IN T02117 TAFII18; human, Homo sapiens. IN T02118 TAFII30; human, Homo sapiens. IN T00782 TAFII55; human, Homo sapiens. IN T00783 TAFII70-alpha; human, Homo sapiens. IN T02208 TAFII70-gamma; human, Homo sapiens. IN T09103 TAFII70; human, Homo sapiens. IN T00794 TBP; human, Homo sapiens. IN T00818 TFIIB; human, Homo sapiens. IN T00894 Vmw65; HSV-1, herpes simplex virus type 1. XX DR TRANSPATH: MO000026173. DR UniProtKB: Q16594; DR UniProtKB: Q9Y3D8; KAD6_HUMAN. XX RN [1]; RE0005527. RX PUBMED: 7597030. RA Klemm R. D., Goodrich J. A., Zhou S., Tjian R. RT Molecular cloning and expression of the 32-kDa subunit of human TFIID reveals interactions with VP16 and TFIIB that mediate transcriptional activation RL Proc. Natl. Acad. Sci. USA 92:5788-5792 (1995). RN [2]; RE0005591. RX PUBMED: 7667268. RA Hisatake K., Ohta T., Takada R., Guermah M., Horikoshi M., Nakatani Y., Roeder R. G. RT Evolutionary conservation of human TATA-binding-polypeptide-associated factors TAFII31 and TAFII80 and interactions of TAFII80 with other TAFs and with general transcription factors RL Proc. Natl. Acad. Sci. USA 92:8195-8199 (1995). RN [3]; RE0005592. RX PUBMED: 7761466. RA Lu H., Levine A. J. RT Human TAFII31 protein is a transcriptional coactivator of the p53 protein RL Proc. Natl. Acad. Sci. USA 92:5154-5158 (1995). RN [4]; RE0005593. RX PUBMED: 8401585. RA Adams M. D., Soares M. B., Kerlavage A. R., Fields C., Venter J. C. RT Rapid cDNA sequencing (expressed sequence tags) from a directionally cloned human infant brain cDNA library RL Nat. Genet. 4:373-380 (1993). RN [5]; RE0017024. RX PUBMED: 10449590. RA Pan S., Sehnke P. C., Ferl R. J., Gurley W. B. RT Specific interactions with TBP and TFIIB in vitro suggest that 14-3-3 proteins may participate in the regulation of transcription when part of a DNA binding complex RL Plant Cell 11:1591-1602 (1999). RN [6]; RE0022565. RX PUBMED: 9171108. RA Fontes J. D., Jiang B., Peterlin B. M. RT The class II trans-activator CIITA interacts with the TBP-associated factor TAFII32. RL Nucleic Acids Res. 25:2522-2528 (1997). RN [7]; RE0022568. RX PUBMED: 9177216. RA Mahanta S. K., Scholl T., Yang F. C., Strominger J. L. RT Transactivation by CIITA, the type II bare lymphocyte syndrome-associated factor, requires participation of multiple regions of the TATA box binding protein. RL Proc. Natl. Acad. Sci. USA 94:6324-6329 (1997). RN [8]; RE0047693. RX PUBMED: 15489227. RA Buss H., Dorrie A., Schmitz M. L., Hoffmann E., Resch K., Kracht M. RT Constitutive and interleukin-1-inducible phosphorylation of p65 NF-{kappa}B at serine 536 is mediated by multiple protein kinases including I{kappa}B kinase (IKK)-{alpha}, IKK{beta}, IKK{epsilon}, TRAF family member-associated (TANK)-binding kinase 1 (TBK1), and an unknown kinase and couples p65 to TATA-binding protein-associated factor II31-mediated interleukin-8 transcription. RL J. Biol. Chem. 279:55633-55643 (2004). RN [9]; RE0047694. RX PUBMED: 14769800. RA Jin Y., Zeng S. X., Lee H., Lu H. RT MDM2 mediates p300/CREB-binding protein-associated factor ubiquitination and degradation. RL J. Biol. Chem. 279:20035-20043 (2004). RN [10]; RE0047995. RX PUBMED: 10821850. RA Choi Y., Asada S., Uesugi M. RT Divergent hTAFII31-binding motifs hidden in activation domains. RL J. Biol. Chem. 275:15912-15916 (2000). RN [11]; RE0048322. RX PUBMED: 15899866. RA Frontini M., Soutoglou E., Argentini M., Bole-Feysot C., Jost B., Scheer E., Tora L. RT TAF9b (formerly TAF9L) is a bona fide TAF that has unique and overlapping roles with TAF9. RL Mol. Cell. Biol. 25:4638-4649 (2005). RN [12]; RE0049260. RX PUBMED: 12101418. RA Lan K. H., Sheu M. L., Hwang S. J., Yen S. H., Chen S. Y., Wu J. C., Wang Y. J., Kato N., Omata M., Chang F. Y., Lee S. D. RT HCV NS5A interacts with p53 and inhibits p53-mediated apoptosis. RL Oncogene 21:4801-4811 (2002). RN [13]; RE0063261. RX PUBMED: 16169070. RA Stelzl U., Worm U., Lalowski M., Haenig C., Brembeck F. H., Goehler H., Stroedicke M., Zenkner M., Schoenherr A., Koeppen S., Timm J., Mintzlaff S., Abraham C., Bock N., Kietzmann S., Goedde A., Toksoz E., Droege A., Krobitsch S., Korn B., Birchmeier W., Lehrach H., Wanker E. E. RT A human protein-protein interaction network: a resource for annotating the proteome. RL Cell 122:957-968 (2005). RN [14]; RE0064710. RX PUBMED: 15932940. RA Palhan V. B., Chen S., Peng G. H., Tjernberg A., Gamper A. M., Fan Y., Chait B. T., La Spada A. R., Roeder R. G. RT Polyglutamine-expanded ataxin-7 inhibits STAGA histone acetyltransferase activity to produce retinal degeneration. RL Proc. Natl. Acad. Sci. USA 102:8472-8477 (2005). RN [15]; RE0074383. RX PUBMED: 19112178. RA Zhang L. J., Liu X., Gafken P. R., Kioussi C., Leid M. RT A chicken ovalbumin upstream promoter transcription factor I (COUP-TFI) complex represses expression of the gene encoding tumor necrosis factor alpha-induced protein 8 (TNFAIP8). RL J. Biol. Chem. 284:6156-6168 (2009). XX //