AC T02118
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ID T02118
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DT 21.05.1997 (created); hiwi.
DT 15.05.2014 (updated); ili.
CO Copyright (C), QIAGEN.
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FA TAFII30
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SY TAF-30; TAF10; TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa; TAF2A; TAF2H; TAFII30; TBP-associated factor 30.
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G004690 TAF10; HGNC: TAF10.
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SF homooligomerizes and interacts with TBP and, weakly, with TAF(II)250 [4];
SF calculated pI = 9.2 [4];
SF no sequence similarity with either Drosophila TAFII30-alpha or TAFII30-beta [4];
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FF part of that TFIID complex which is specifically found in one certain phosphocellulose fraction during purification (PC1.0, but not in PC0.3) [4];
FF involved in mediating trans-activation by the AF-2 domain of estrogen receptor T00261 [4];
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IN T00261 ER-alpha; human, Homo sapiens.
IN T34366 SAP130; human, Homo sapiens.
IN T02116 TAF2J; human, Homo sapiens.
IN T00784 TAFII100; human, Homo sapiens.
IN T28810 TAFII135; human, Homo sapiens.
IN T02117 TAFII18; human, Homo sapiens.
IN T00781 TAFII250-isoform2; human, Homo sapiens.
IN T02118 TAFII30; human, Homo sapiens.
IN T02113 TAFII31; human, Homo sapiens.
IN T00782 TAFII55; human, Homo sapiens.
IN T00783 TAFII70-alpha; human, Homo sapiens.
IN T09103 TAFII70; human, Homo sapiens.
IN T00794 TBP; human, Homo sapiens.
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DR TRANSPATH: MO000026178.
DR UniProtKB: Q12962;
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RN [1]; RE0005530.
RX PUBMED: 8441620.
RA Brou C., Wu J., Ali S., Scheer E., Lang C., Davidson I., Chambon P., Tora L.
RT Different TBP-associated factors are requred for mediating the stimulation of transcription in vitro by the acidic transactivator GAL--VP16 and the two nonacidic activation functions of the estrogen receptor
RL Nucleic Acids Res. 21:5-12 (1993).
RN [2]; RE0005531.
RX PUBMED: 8530084.
RA Scheer E., Mattei M. G., Jacq X., Chambon P., Toral L.
RT Organization and chromosomal localization of the gene (TAF2H) encoding the human TBP-associated factor II 30 (TAFII30)
RL Genomics 29:269-272 (1995).
RN [3]; RE0005551.
RX PUBMED: 8440239.
RA Brou C., Chaudhary S., Davidson I., Lutz Y., Wu J., Egly J.-M., Tora L., Chambon P.
RT Distinct TFIID complexes mediate the effect of different transcriptional activators
RL EMBO J. 12:489-499 (1993).
RN [4]; RE0005562.
RX PUBMED: 7923369.
RA Jacq X., Brou C., Lutz Y., Davidson I., Chambon P., Tora L.
RT Human TAFII30 is present in a distinct TFIID complex and is required for transcriptional activation by the estrogen receptor
RL Cell 79:107-117 (1994).
RN [5]; RE0045374.
RX PUBMED: 15115762.
RA Helmlinger D., Hardy S., Sasorith S., Klein F., Robert F., Weber C., Miguet L., Potier N., Van-Dorsselaer A., Wurtz J. M., Mandel J. L., Tora L., Devys D.
RT Ataxin-7 is a subunit of GCN5 histone acetyltransferase-containing complexes
RL Hum. Mol. Genet. 13:1257-65 (2004).
RN [6]; RE0047416.
RX PUBMED: 12034840.
RA Benecke A., Gaudon C., Garnier J. M., vom Baur E., Chambon P., Losson R.
RT ADA3-containing complexes associate with estrogen receptor alpha.
RL Nucleic Acids Res. 30:2508-2514 (2002).
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