AC T00782
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ID T00782
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DT 14.04.1993 (created); ewi.
DT 08.01.2014 (updated); yre.
CO Copyright (C), QIAGEN.
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FA TAFII55
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SY TAF(II)55; TAF-50; TAF-55; TAF2F; TAF7; TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa; TAFII55; TBP-associated factor 55.
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G004666 TAF7; HGNC: TAF7.
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SF no obvious sequence homology with any previously known protein found [4];
SF 40% charged residues [4];
SF interacts with several upstream activators, but not with NF-kappaB1 (p50), CP2, VP16, or E2 (HPV-11) [4];
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CP ubiquitous [4].
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FF part of TFIID complex D-TFIID [4] [1] [2];
FF confers interaction of TFIID with several upstream activators [4];
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IN T30638 BRD4; human, Homo sapiens.
IN T14184 Cdx-1; mouse, Mus musculus.
IN T00759 Sp1; human, Homo sapiens.
IN T02116 TAF2J; human, Homo sapiens.
IN T00784 TAFII100; human, Homo sapiens.
IN T28810 TAFII135; human, Homo sapiens.
IN T02117 TAFII18; human, Homo sapiens.
IN T00781 TAFII250-isoform2; human, Homo sapiens.
IN T08956 TAFII250; human, Homo sapiens.
IN T02114 TAFII28; human, Homo sapiens.
IN T02118 TAFII30; human, Homo sapiens.
IN T02113 TAFII31; human, Homo sapiens.
IN T09103 TAFII70; human, Homo sapiens.
IN T00792 tat; HIV-1, human immunodeficiency virus type 1.
IN T08520 TBP-isoform1; human, Homo sapiens.
IN T05140 trrap; human, Homo sapiens.
IN T00874 USF1; human, Homo sapiens.
IN T00915 YY1; human, Homo sapiens.
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DR TRANSPATH: MO000025168.
DR UniProtKB: Q15545;
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RN [1]; RE0000746.
RX PUBMED: 1398073.
RA Zhou Q., Lieberman P. M., Boyer T. G., Berk A. J.
RT Holo-TFIID supports transcriptional stimulation by diverse activators and from a TATA-less promoter
RL Genes Dev. 6:1964-1974 (1992).
RN [2]; RE0002495.
RX PUBMED: 1387711.
RA Timmers H. T. M., Meyers R. E., Sharp P. A.
RT Composition of transcription factor B-TFIID
RL Proc. Natl. Acad. Sci. USA 89:8140-8144 (1992).
RN [3]; RE0005507.
RX PUBMED: 8758937.
RA Dubrovskaya V., Lavigne A.-C., Davidson I., Acker J., Staub A., Tora L.
RT Distinct domains of hTAFII100 are requireed for functional interactions with transcription factor TFIIbeta (RAP30) and incorporation into the TFIID complex
RL EMBO J. 15:3702-3712 (1996).
RN [4]; RE0005526.
RX PUBMED: 7824954.
RA Chiang C.-M., Roeder R. G.
RT Cloning of an instrinsic human TFIID subunit that interacts with multiple transcriptional activators
RL Science 267:531-536 (1995).
RN [5]; RE0052321.
RX PUBMED: 17158164.
RA Calon A., Gross I., Davidson I., Kedinger M., Duluc I., Domon-Dell C., Freund J. N.
RT Functional interaction between the homeoprotein CDX1 and the transcriptional machinery containing the TATA-binding protein.
RL Nucleic Acids Res. 35:175-185 (2007).
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