AC T05140
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ID T05140
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DT 30.05.2002 (created); spi.
DT 15.05.2014 (updated); ili.
CO Copyright (C), QIAGEN.
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FA trrap
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SY PAF400; TR-AP; transformation/transcription domain-associated protein; TRRAP.
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G004312 TRRAP; HGNC: TRRAP.
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IN T06126 BAF53a; human, Homo sapiens.
IN T00140 c-Myc-isoform1; human, Homo sapiens.
IN T01542 E2F-1; human, Homo sapiens.
IN T09570 E2F-1; Mammalia.
IN T17403 E2F-2; Mammalia.
IN T17404 E2F-3; Mammalia.
IN T01686 GCN5; human, Homo sapiens.
IN T06376 ING1; human, Homo sapiens.
IN T22586 N-Myc; Mammalia.
IN T03214 Pontin52; human, Homo sapiens.
IN T09098 SREBP-2-isoform1; human, Homo sapiens.
IN T28810 TAFII135; human, Homo sapiens.
IN T00782 TAFII55; human, Homo sapiens.
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DR TRANSPATH: MO000031369.
DR UniProtKB: Q9Y4A5; Q9Y6H4.
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RN [1]; RE0017841.
RX PUBMED: 9708738.
RA McMahon S. B., Van Buskirk H. A., Dugan K. A., Copeland T. D., Cole M. D.
RT The novel ATM-related protein TRRAP is an essential cofactor for the c-Myc and E2F oncoproteins.
RL Cell 94:363-374 (1998).
RN [2]; RE0027531.
RX PUBMED: 10882073.
RA Wood M. A., McMahon S. B., Cole M. D.
RT An ATPase/helicase complex is an essential cofactor for oncogenic transformation by c-Myc.
RL Mol. Cell 5:321-30 (2000).
RN [3]; RE0029177.
RX PUBMED: 11839798.
RA Park J., Wood M. A., Cole M. D.
RT BAF53 forms distinct nuclear complexes and functions as a critical c-Myc-interacting nuclear cofactor for oncogenic transformation.
RL Mol. Cell. Biol. 22:1307-16 (2002).
RN [4]; RE0029643.
RX PUBMED: 12015309.
RA Vieyra D., Loewith R., Scott M., Bonnefin P., Boisvert F. M., Cheema P., Pastyryeva S., Meijer M., Johnston R. N., Bazett-Jones D. P., McMahon S., Cole M. D., Young D., Riabowol K.
RT Human ING1 proteins differentially regulate histone acetylation.
RL J. Biol. Chem. 277:29832-9 (2002).
RN [5]; RE0048322.
RX PUBMED: 15899866.
RA Frontini M., Soutoglou E., Argentini M., Bole-Feysot C., Jost B., Scheer E., Tora L.
RT TAF9b (formerly TAF9L) is a bona fide TAF that has unique and overlapping roles with TAF9.
RL Mol. Cell. Biol. 25:4638-4649 (2005).
RN [6]; RE0051146.
RX PUBMED: 15649435.
RA Unno A., Takada I., Takezawa S., Oishi H., Baba A., Shimizu T., Tokita A., Yanagisawa J., Kato S.
RT TRRAP as a hepatic coactivator of LXR and FXR function.
RL Biochem. Biophys. Res. Commun. 327:933-938 (2005).
RN [7]; RE0055135.
RX PUBMED: 18542057.
RA Araki K., Kawauchi K., Tanaka N.
RT IKK/NF-kappaB signaling pathway inhibits cell-cycle progression by a novel Rb-independent suppression system for E2F transcription factors.
RL Oncogene 27:5696-5705 (2008).
RN [8]; RE0064710.
RX PUBMED: 15932940.
RA Palhan V. B., Chen S., Peng G. H., Tjernberg A., Gamper A. M., Fan Y., Chait B. T., La Spada A. R., Roeder R. G.
RT Polyglutamine-expanded ataxin-7 inhibits STAGA histone acetyltransferase activity to produce retinal degeneration.
RL Proc. Natl. Acad. Sci. USA 102:8472-8477 (2005).
RN [9]; RE0067198.
RX PUBMED: 16387653.
RA Doyon Y., Cayrou C., Ullah M., Landry A. J., Cote V., Selleck W., Lane W. S., Tan S., Yang X. J., Cote J.
RT ING tumor suppressor proteins are critical regulators of chromatin acetylation required for genome expression and perpetuation.
RL Mol. Cell 21:51-64 (2006).
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