AC T02208
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ID T02208
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DT 29.07.1997 (created); ewi.
DT 06.08.2013 (updated); mkl.
CO Copyright (C), QIAGEN.
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FA TAFII70-gamma
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SY TAF(II)78; TAF(II)80; TAF-70; TAF-80; TBP-associated factor 70 gamma.
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G004667 TAF6; HGNC: TAF6.
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HO TAF(II)60 (Drosophila).
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SZ 667 AA; 71.5 kDa (cDNA) (calc.).
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SQ MAEEKKLKLSNTVLPSESMKVVAESMGIAQIQEETCQLLTDEVSYRIKEIAQDALKFMHM
SQ GKRQKLTTSDIDYALKLKNVEPLYGFHAQEFIPFRFASGGGRELYFYEEKEVDLSDIINT
SQ PLPRVPLDVCLKAHWLSIEGCQPAIPENPPPAPKEQQKAEATEPLKSAKPGQEEDGPLKG
SQ KGQGATTADGKGKEKKAPPLLEGAPLRLKPRSIHELSVEQQLYYKEITEACVGSCEAKRA
SQ EALQSIATDPGLYQMLPRFSTFISEGVRVNVVQNNLALLIYLMRMVKALMDNPTLYLEKY
SQ VHELIPAVMTCIVSRQLCLRPDVDNHWALRDFAARLVAQICKHFSTTTNNIQSRITKTFT
SQ KSWVDEKTPWTTRYGSIAGLAELGHDVIKTLILPRLQQEGERIRSVLDGPVLSNIDRIGA
SQ DHVQSLLLKHCAPVLAKLRPPPDNQDAYRAEFGSLGPLLCSQVVKARAQAALQAQQPRPT
SQ LTLSQAPQPGPRTPGLLKVPGSIALPVQTLVSARAAAPPQPSPPPTKFIVMSSSSSAPST
SQ QQVLSLSTSAPGSGSTTTSPVTTTVPSVQPIVKLVSTATTAPPSTAPSGPGSVQKYIVVS
SQ LPPTGEGKGGPTSHPSPVPPPASSPSPLSGSALCGGKQEAGDSPPPAPGTPKANGSQPNS
SQ GSPQPAP
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SC edited Swiss-Prot #P49848
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FT 1 100 
binding to TAF(II)31 and TAF(II)20 (by homology) [2].
FT 12 78 
PF02969; TATA box binding protein associated factor (.
FT 15 78 
PS50028; HIST_TAF.
FT 82 458 
PF00478; IMP dehydrogenase / GMP reductase domain.
FT 203 276 
binding to TAF(II)250 and TFIIF-alpha (by homology) [2].
FT 304 402 
PF07571; Protein of unknown function (DUF1546).
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SF splice variants are TAF(II)-alpha and -beta [1];
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IN T02116 TAF2J; human, Homo sapiens.
IN T00781 TAFII250-isoform2; human, Homo sapiens.
IN T02113 TAFII31; human, Homo sapiens.
IN T02168 TFIIF-alpha; human, Homo sapiens.
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DR TRANSPATH: MO000026226.
DR UniProtKB: P49848-2;
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RN [1]; RE0005560.
RX PUBMED: 8262073.
RA Weinzierl R. O. J., Ruppert S., Dynlacht B. D., Tanese N., Tjian R.
RT Cloning and expression of Drosophila TAFII60 and human TAFII70 reveal conserved interactions with other subunits of TFIID
RL EMBO J. 12:5303-5309 (1993).
RN [2]; RE0005591.
RX PUBMED: 7667268.
RA Hisatake K., Ohta T., Takada R., Guermah M., Horikoshi M., Nakatani Y., Roeder R. G.
RT Evolutionary conservation of human TATA-binding-polypeptide-associated factors TAFII31 and TAFII80 and interactions of TAFII80 with other TAFs and with general transcription factors
RL Proc. Natl. Acad. Sci. USA 92:8195-8199 (1995).
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//