AC T15045
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ID T15045
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DT 28.08.2008 (created); jtr.
DT 19.03.2015 (updated); pro.
CO Copyright (C), QIAGEN.
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FA nanog
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SY hNanog; Homeobox protein NANOG; Homeobox transcription factor Nanog; Nanog; Nanog homeobox.
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G048863 NANOG; HGNC: Nanog.
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CL C0006; homeo; 3.1.2.12.1.
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FF Overexpression of Nanog in ES (Embryonic stem) cells resulted in increase of reprogramming and cloning efficiency and also increases the survival rate of early reprogrammed cells. [3];
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IN T01493 STAT3; human, Homo sapiens.
IN T18218 STAT3{pY705}; human, Homo sapiens.
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MX M01123 V$NANOG_01.
MX M01247 V$NANOG_02.
MX M04837 V$NANOG_05.
MX M04891 V$NANOG_06.
MX M04898 V$NANOG_07.
MX M07327 V$NANOG_Q3.
MX M07362 V$NANOG_Q6.
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BS R66845.
BS R64343.
BS R62919.
BS R72302.
BS R58039.
BS R38503.
BS R38504.
BS R38506.
BS R38507.
BS R25262.
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DR TRANSPATH: MO000134485.
DR UniProtKB: Q9H9S0;
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RN [1]; RE0054287.
RX PUBMED: 18039466.
RA Kochupurakkal B. S., Sarig R., Fuchs O., Piestun D., Rechavi G., Givol D.
RT Nanog inhibits the switch of myogenic cells towards the osteogenic lineage.
RL Biochem. Biophys. Res. Commun. 365:846-850 (2008).
RN [2]; RE0055244.
RX PUBMED: 18441325.
RA Bourguignon L. Y., Peyrollier K., Xia W., Gilad E.
RT Hyaluronan-CD44 interaction activates stem cell marker Nanog, Stat-3-mediated MDR1 gene expression, and ankyrin-regulated multidrug efflux in breast and ovarian tumor cells.
RL J. Biol. Chem. 283:17635-17651 (2008).
RN [3]; RE0064994.
RX PUBMED: 18029452.
RA Yu J., Vodyanik M. A., Smuga-Otto K., Antosiewicz-Bourget J., Frane J. L., Tian S., Nie J., Jonsdottir G. A., Ruotti V., Stewart R., Slukvin I. I., Thomson J. A.
RT Induced pluripotent stem cell lines derived from human somatic cells.
RL Science 318:1917-1920 (2007).
RN [4]; RE0066003.
RX PUBMED: 19718018.
RA Kim J. B., Greber B., Arauzo-Bravo M. J., Meyer J., Park K. I., Zaehres H., Scholer H. R.
RT Direct reprogramming of human neural stem cells by OCT4.
RL Nature 461:649-643 (2009).
RN [5]; RE0068365.
RX PUBMED: 19522013.
RA Chan K. K., Zhang J., Chia N. Y., Chan Y. S., Sim H. S., Tan K. S., Oh S. K., Ng H. H., Choo A. B.
RT KLF4 and PBX1 directly regulate NANOG expression in human embryonic stem cells.
RL Stem Cells 27:2114-2125 (2009).
RN [6]; RE0072535.
RX PUBMED: 18568018.
RA Varelas X., Sakuma R., Samavarchi-Tehrani P., Peerani R., Rao B. M., Dembowy J., Yaffe M. B., Zandstra P. W., Wrana J. L.
RT TAZ controls Smad nucleocytoplasmic shuttling and regulates human embryonic stem-cell self-renewal.
RL Nat. Cell Biol. 10:837-848 (2008).
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