AC T19194
XX
ID T19194
XX
DT 20.11.2002 (created); cch.
DT 07.03.2012 (updated); mkl.
CO Copyright (C), QIAGEN.
XX
FA PRIC285
XX
SY KIAA1769; peroxisomal proliferator-activated receptor A interacting complex 285; peroxisomal proliferator-activated receptor A interacting complex 285 kDa protein; PPAR-alpha interacting complex protein 285.
XX
OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
XX
GE G006581 HELZ2; HGNC: HELZ2.
XX
SZ 2114 AA; 235.1 kDa (cDNA) (calc.).
XX
SQ LTSDSQTRAVLRGSSAGHTVGALADSTEAPSKKPMSSSPSRSAADIYIREYFHSHVSGGH
SQ PEATPLRVMYTDRPLSQTDPVTLQYCCLTDDRQAFRPPTRAELARHRVVVTTTSQARELR
SQ VPVGFFSHILIDEAAQMLECEALTPLAYASHGTRLVLAGDHMQVTPRLFSVARARAAEHT
SQ LLHRLFLCYQQETHEVARQSRLVFHENYRCTDAIVSFISRHFYVAKGNPIHARGKVPPHP
SQ RHYPLMFCHVAGNPDRDMSMASWLNLAEIAQVVEKVQEAYNTWPSCWGGREQRCICVVSH
SQ GAQVSALRQELRRRDLGQVSVGSFEILPGRQFRVVVLSTVHTCQSLLSPGALAPEFFTDA
SQ RVLNTVLTRAQSQLVVVGDAVALCSFGACGKLWESFIRECVERHSVCPEGLSMEQVEQGV
SQ AQRRRWPPRGTQAGAAGNWEAAPEPVGDLAEEQAAVVTAMVKAEPGDEALSPASRDITAT
SQ TAQTEAAAAPAGDAVKEDVVPGACAAGAAAAAGVESTEAEDAEADFWPWDGELNADDAIL
SQ RELLDESQKVMVTVGEDGLLDTVARPESLQQARLYENLPPAALRKLLRAEPERYRHCSFV
SQ PETFERASAIPLDDASSGPIQVRGRLDCGMAFAGDEVLVQLLSGDKAPEGRLRGRVLGVL
SQ KRKRHELAFVCRMDTWDPRIMVPINGSVTKIFVAELKDPSQVPIYSLRKGRLQRVGLERL
SQ TAEARHSRLFWVQIVLWRQGFYYPLGIVREVLPEASTWEQGLRILGLEYSLRVPPSDQAT
SQ ITKVLQKYHTELGRVAGRREDCRAFLTFTVDPQGACNLDDALSVRDLGPRCEVAVHITDV
SQ ASFVPRDGVLDVEARRQGAAFYAPGREPVPMLPASLCQDVLSLLPGRDRLAISLFLTMEK
SQ ASGQLKSLRFAPSVVQSDRQLSYEEAEEVIRQHPGAGRELPARLDSVDACVVAACYFSRL
SQ LRRHRLRSDCFYEQPDEDGTLGFRAAHIMVKEYMIQFNRLVAEFLVGSECTRTVTPLRWQ
SQ PAPRSQQLKALCEKHGDRVPLSLHLGHHLHGGGGSPPDTRLHLLASLWKQVQFAARTQDY
SQ EQMVDLVTTDDMHPFLAPAGRDLRKALERSAFGRCARGHQQQGGHYSLQVDWYTWATSPI
SQ RRYLDVVLQRQILLALGHGGSAYSARDIDGLCQAFSLQHALAQSYQRRARSLHLAVQLKA
SQ QPLDKLGFVVDVEAGSRCFRLLFPSNRETLPDPCPVPYGSLQLAEHPHALAGRPGLRLLW
SQ RRRVYSAQGSSPPLPLPGTVPDPHTLAVETALWKQLLELVELQRWPEAAALIQEKGEASQ
SQ RRELVQVQRSHCGHFLEVARELGSGDTLQVQLGTSLQHGFLVPSPQLWTVAPGFSLCLEH
SQ VERPGDCFSGRVYRAPRDRYRDVDEYACVWEPFCALESATGAVAENDSVTLQHLSVSWEA
SQ SRTPQGQLQGAFRLEAAFLEENCADINFSCCYLCIRLEGLLAPTASPRPGPSSLGPGLNV
SQ DPGTYTWVAHGQTEDWDQERRADRQEAPRRVHLFVHHMGMEKVPEEVLRPGTLFTVELLP
SQ KQLPDLRKEEAVRGLEEASPLVTSIALGRPVPQPLCRVIPSRFLERQTYNIPGGRHKLNP
SQ SQNVAVREALEKPFTVIQGPPGTGKTIVGLHIVFWFHKSNQEQVQPGGPPRGEKRLGGPC
SQ ILYCGPSNKSVDVLAGLLLRRMELKPLRVYSEQAEASEFPVPRVGSRKLLRKSPREGRPN
SQ QSLRSITLHHRIRQAPNPYSSEIKAFDTRLQRGELFSREDLVWYKKVLWEARKFELDRHE
SQ VILCTCSCAASASLKILDVRQILVDEAGMATEPETLIPLVQFPQAEKVVLLGDHKQLRPV
SQ VKNERLQNLGLDRSLFERYHEDAHMLDTQYRMHEGICAFPSVAFYKSKLKTWQGLRRPPS
SQ VLGHAGKESCPVIFGHVQGHERSLLVSTDEGNENSKANLEEVAEVVRITKQLTLGRTVEP
SQ QDIAVLTPYNAQASEISKALRREGIAGVAVSSITKSQGSEWRYVLVSTVRTCAKSDLDQR
SQ PTKSWLKKFLGFVVDPNQVNVAVTRAQEGLCLIGDHLLLRCCPLWRSLLDFCEAQQTLVP
SQ AGQVRVCRRPTMPS
XX
SC translated from EMBL:AB051556
XX
FT 506 510 
LXXLL motif 1 [1].
FT 549 553 
LXXLL motif 2 [1].
FT 604 608 
LXXLL motif 3 [1].
FT 800 1020 
PF00773; RNB.
FT 1443 1447 
LXXLL motif 4 [1].
FT 1660 1664 
LXXLL motif 5 [1].
XX
EX colon,,,adult; detectable; Northern blot; RNA (undefined); [1].
EX kidney (right and left),,,adult; detectable; Northern blot; RNA (undefined); [1].
EX liver,,,adult; detectable; Northern blot; RNA (undefined); [1].
EX lung (right and left),,,adult; detectable; Northern blot; RNA (undefined); [1].
EX muscles,,,adult; detectable; Northern blot; RNA (undefined); [1].
EX placenta,,,adult; detectable; Northern blot; RNA (undefined); [1].
EX spleen,,,adult; detectable; Northern blot; RNA (undefined); [1].
XX
IN T00694 PPARalpha; mouse, Mus musculus.
IN T05347 PPARgamma; mouse, Mus musculus.
XX
DR TRANSPATH: MO000033674.
DR EMBL: AB051556;
DR UniProtKB: Q9BYK8-4;
XX
RN [1]; RE0018238.
RX PUBMED: 12189208.
RA Surapureddi S., Yu S., Bu H., Hashimoto T., Yeldandi A. V., Kashireddy P., Cherkaoui-Malki M., Qi C., Zhu Y. J., Rao M. S., Reddy J. K.
RT Identification of a transcriptionally active peroxisome proliferator-activated receptor alpha -interacting cofactor complex in rat liver and characterization of PRIC285 as a coactivator.
RL Proc. Natl. Acad. Sci. USA 99:11836-11841 (2002).
XX
//