TRANSFAC FACTOR TABLE, Release 2017.2 - public - 2017-06-30, (C) QIAGEN

AC T22415 XX ID T22415 XX DT 14.12.2001 (created); ili. DT 26.06.2013 (updated); prb. CO Copyright (C), QIAGEN. XX FA Sp100 XX SY Lysp100b; Nuclear autoantigen Sp-100; Nuclear dot-associated Sp100 protein; Speckled, 100 kDa. XX OS human, Homo sapiens OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates XX GE G002945 SP100; HGNC: SP100. XX CL C0077; SAND; XX SF several isoforms; XX FF disrupts Bright binding to MAR-DNA at equivalent concentrations [1]; FF repression of Bright depends on the "conserved domain" [1]; FF nuclear autoantigen that localizes to promyelocytic leukemia (PML) nuclear bodies [1]; XX IN T00112 c-Ets-1A; human, Homo sapiens. IN T09585 CREM; human, Homo sapiens. IN T06432 DRI1; mouse, Mus musculus. XX DR TRANSPATH: MO000056127. DR SMARTDB: SB000069. DR UniProtKB: P23497; XX RN [1]; RE0017413. RX PUBMED: 10921892. RA Zong R.-T., Das C., Tucker P. W. RT Regulation of matrix attachment region-dependent, lymphocyte-restricted transcription through differential localization within promyelocytic leukemia nuclear bodies RL EMBO J. 19:4123-4133 (2000). RN [2]; RE0048001. RX PUBMED: 11909962. RA Wasylyk C., Schlumberger S. E., Criqui-Filipe P., Wasylyk B. RT Sp100 interacts with ETS-1 and stimulates its transcriptional activity. RL Mol. Cell. Biol. 22:2687-2702 (2002). RN [3]; RE0048458. RX PUBMED: 9412458. RA Sternsdorf T., Jensen K., Will H. RT Evidence for covalent modification of the nuclear dot-associated proteins PML and Sp100 by PIC1/SUMO-1. RL J. Cell Biol. 139:1621-1634 (1997). RN [4]; RE0048810. RX PUBMED: 17000644. RA Vertegaal A. C., Andersen J. S., Ogg S. C., Hay R. T., Mann M., Lamond A. I. RT Distinct and overlapping sets of SUMO-1 and SUMO-2 target proteins revealed by quantitative proteomics. RL Mol. Cell. Proteomics 5:2298-2310 (2006). RN [5]; RE0066609. RX PUBMED: 17062732. RA Vlasakova J., Novakova Z., Rossmeislova L., Kahle M., Hozak P., Hodny Z. RT Histone deacetylase inhibitors suppress IFNalpha-induced up-regulation of promyelocytic leukemia protein. RL Blood 109:1373-1380 (2007). XX //