AC T22417
XX
ID T22417
XX
DT 24.01.2006 (created); rad.
DT 29.10.2013 (updated); yre.
CO Copyright (C), QIAGEN.
XX
FA SRC-1E
XX
SY F-SRC-1; Hin-2 protein; NCOA-1; NCOA1; nuclear receptor coactivator 1; RIP160; SRC-1; SRC1; steroid receptor coactivator-1.
XX
OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
XX
GE G002755 NCOA1; HGNC: NCOA1.
XX
CL C0010; bHLH; 1.2.5.3.1.2.
XX
SZ 1399 AA; 152.4 kDa (cDNA) (calc.).
XX
SQ MSGLGDSSSDPANPDSHKRKGSPCDTLASSTEKRRREQENKYLEELAELLSANISDIDSL
SQ SVKPDKCKILKKTVDQIQLMKRMEQEKSTTDDDVQKSDISSSSQGVIEKESLGPLLLEAL
SQ DGFFFVVNCEGRIVFVSENVTSYLGYNQEELMNTSVYSILHVGDHAEFVKNLLPKSLVNG
SQ VPWPQEATRRNSHTFNCRMLIHPPDEPGTENQEACQRYEVMQCFTVSQPKSIQEDGEDFQ
SQ SCLICIARRLPRPPAITGVESFMTKQDTTGKIISIDTSSLRAAGRTGWEDLVRKCIYAFF
SQ QPQGREPSYARQLFQEVMTRGTASSPSYRFILNDGTMLSAHTKCKLCYPQSPDMQPFIMG
SQ IHIIDREHSGLSPQDDTNSGMSIPRVNPSVNPSISPAHGVARSSTLPPSNSNMVSTRINR
SQ QQSSDLHSSSHSNSSNSQGSFGCSPGSQIVANVALNQGQASSQSSNPSLNLNNSPMEGTG
SQ ISLAQFMSPRRQVTSGLATRPRMPNNSFPPNISTLSSPVGMTSSACNNNNRSYSNIPVTS
SQ LQGMNEGPNNSVGFSASSPVLRQMSSQNSPSRLNIQPAKAESKDNKEIASILNEMIQSDN
SQ SSSDGKPLDSGLLHNNDRLSDGDSKYSQTSHKLVQLLTTTAEQQLRHADIDTSCKDVLSC
SQ TGTSNSASANSSGGSCPSSHSSLTERHKILHRLLQEGSPSDITTLSVEPDKKDSASTSVS
SQ VTGQVQGNSSIKLELDASKKKESKDHQLLRYLLDKDEKDLRSTPNLSLDDVKVKVEKKEQ
SQ MDPCNTNPTPMTKPTPEEIKLEAQSQFTADLDQFDQLLPTLEKAAQLPGLCETDRMDGAV
SQ TSVTIKSEILPASLQSATARPTSRLNRLPELELEAIDNQFGQPGTGDQIPWTNNTVTAIN
SQ QSKSEDQCISSQLDELLCPPTTVEGRNDEKALLEQLVSFLSGKDETELAELDRALGIDKL
SQ VQGGGLDVLSERFPPQQATPPLIMEERPNLYSQPYSSPSPTANLPSPFQGMVRQKPSLGT
SQ MPVQVTPPRGAFSPGMGMQPRQTLNRPPAAPNQLRLQLQQRLQGQQQLIHQNRQAILNQF
SQ AATAPVGINMRSGMQQQITPQPPLNAQMLAQRQRELYSQQHRQRQLIQQQRAMLMRQQSF
SQ GNNLPPSSGLPVQMGNPRLPQGAPQQFPYPPNYGTNPGTPPASTSPFSQLAANPEASLAN
SQ RNSMVSRGMTGNIGGQFGTGINPQMQQNVFQYPGAGMVPQGEANFAPSLSPGSSMVPMPI
SQ PPPQSSLLQQTPPASGYQSPDMKAWQQGAIGNNNVFSQAVQNQPTPAQPGVYNNMSITVS
SQ MAGGNTNVQNMNPMMAQMQMSSLQMPGMNTVCPEQINDPALRHTGLYCNQLSSTDLLKTE
SQ ADGTQDKKTEEFFSVVTTD
XX
SC translated from EMBL:AJ000882
XX
FT 18 81 
PS50888; HLH.
FT 24 81 
PF00010; Helix-loop-helix DNA-binding domain.
FT 29 86 
SM00353; finulus.
FT 53 1390 
PF00478; IMP dehydrogenase / GMP reductase domain.
FT 109 180 
PS50112; PAS.
FT 111 178 
SM00091; pas_2.
FT 633 637 
NR-box motif (LXXLL) [1].
FT 690 694 
NR-box motif (LXXLL) [1].
FT 749 753 
NR-box motif (LXXLL) [1].
FT 1149 1199 
PF07469; Domain of unknown function (DUF1518).
FT 1212 1268 PF07469; Domain of unknown function (DUF1518).
XX
IN T01346 arnt-isoform1; human, Homo sapiens.
IN T27166 BAF57; mouse, Mus musculus.
IN T15118 CBP; Mammalia.
IN T00261 ER-alpha; human, Homo sapiens.
XX
DR TRANSPATH: MO000058418.
DR EMBL: AJ000882; HSJ000882.
DR UniProtKB: Q15788-2;
XX
RN [1]; RE0035978.
RX PUBMED: 10454563.
RA Ma H., Hong H., Huang S. M., Irvine R. A., Webb P., Kushner P. J., Coetzee G. A., Stallcup M. R.
RT Multiple signal input and output domains of the 160-kilodalton nuclear receptor coactivator proteins.
RL Mol. Cell. Biol. 19:6164-6173 (1999).
XX
//