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TRANSFAC FACTOR TABLE, Release 2017.2 - public - 2017-06-30, (C) QIAGEN


AC T22503 XX ID T22503 XX DT 30.11.2009 (created); grs. DT 25.05.2011 (updated); pos. CO Copyright (C), QIAGEN. XX FA IkappaBzeta XX SY FLJ30225; FLJ34463; I-kappa-B-zeta; IkappaBzeta; IkB-zeta; IKBZ; IL-1 inducible nuclear ankyrin-repeat protein; INAP; Mail; MAIL-L; Molecule possessing ankyrin repeats induced by lipopolysaccharide; NF-kappa-B inhibitor zeta; NFKBIZ; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta. XX OS human, Homo sapiens OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates XX GE G034821 NFKBIZ; HGNC: NFKBIZ. XX CL C0020; Rel; 6.1.2.1.5. XX IN T01925 NF-kappaB1; human, Homo sapiens. IN T01493 STAT3; human, Homo sapiens. IN T14458 STAT3; Mammalia. XX DR TRANSPATH: MO000165401. DR UniProtKB: Q9BYH8; XX RN [1]; RE0065019. RX PUBMED: 19707556. RA Raices R. M., Kannan Y., Bellamkonda-Athmaram V., Seshadri S., Wang H., Guttridge D. C., Wewers M. D. RT A novel role for IkappaBzeta in the regulation of IFNgamma production. RL PLoS ONE 4:e6776 (2009). RN [2]; RE0069938. RX PUBMED: 19783680. RA Seshadri S., Kannan Y., Mitra S., Parker-Barnes J., Wewers M. D. RT MAIL regulates human monocyte IL-6 production. RL J. Immunol. 183:5358-5368 (2009). RN [3]; RE0069949. RX PUBMED: 16513645. RA Totzke G., Essmann F., Pohlmann S., Lindenblatt C., Janicke R. U., Schulze-Osthoff K. RT A novel member of the IkappaB family, human IkappaB-zeta, inhibits transactivation of p65 and its DNA binding. RL J. Biol. Chem. 281:12645-12654 (2006). RN [4]; RE0069976. RX PUBMED: 17447895. RA Matsuo S., Yamazaki S., Takeshige K., Muta T. RT Crucial roles of binding sites for NF-kappaB and C/EBPs in IkappaB-zeta-mediated transcriptional activation. RL Biochem. J. 405:605-615 (2007). RN [5]; RE0070219. RX PUBMED: 19595668. RA Wu Z., Zhang X., Yang J., Wu G., Zhang Y., Yuan Y., Jin C., Chang Z., Wang J., Yang X., He F. RT Nuclear protein IkappaB-zeta inhibits the activity of STAT3. RL Biochem. Biophys. Res. Commun. 387:348-352 (2009). XX //