AC T22503
XX
ID T22503
XX
DT 30.11.2009 (created); grs.
DT 25.05.2011 (updated); pos.
CO Copyright (C), QIAGEN.
XX
FA IkappaBzeta
XX
SY FLJ30225; FLJ34463; I-kappa-B-zeta; IkappaBzeta; IkB-zeta; IKBZ; IL-1 inducible nuclear ankyrin-repeat protein; INAP; Mail; MAIL-L; Molecule possessing ankyrin repeats induced by lipopolysaccharide; NF-kappa-B inhibitor zeta; NFKBIZ; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta.
XX
OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
XX
GE G034821 NFKBIZ; HGNC: NFKBIZ.
XX
CL C0020; Rel; 6.1.2.1.5.
XX
IN T01925 NF-kappaB1; human, Homo sapiens.
IN T01493 STAT3; human, Homo sapiens.
IN T14458 STAT3; Mammalia.
XX
DR TRANSPATH: MO000165401.
DR UniProtKB: Q9BYH8;
XX
RN [1]; RE0065019.
RX PUBMED: 19707556.
RA Raices R. M., Kannan Y., Bellamkonda-Athmaram V., Seshadri S., Wang H., Guttridge D. C., Wewers M. D.
RT A novel role for IkappaBzeta in the regulation of IFNgamma production.
RL PLoS ONE 4:e6776 (2009).
RN [2]; RE0069938.
RX PUBMED: 19783680.
RA Seshadri S., Kannan Y., Mitra S., Parker-Barnes J., Wewers M. D.
RT MAIL regulates human monocyte IL-6 production.
RL J. Immunol. 183:5358-5368 (2009).
RN [3]; RE0069949.
RX PUBMED: 16513645.
RA Totzke G., Essmann F., Pohlmann S., Lindenblatt C., Janicke R. U., Schulze-Osthoff K.
RT A novel member of the IkappaB family, human IkappaB-zeta, inhibits transactivation of p65 and its DNA binding.
RL J. Biol. Chem. 281:12645-12654 (2006).
RN [4]; RE0069976.
RX PUBMED: 17447895.
RA Matsuo S., Yamazaki S., Takeshige K., Muta T.
RT Crucial roles of binding sites for NF-kappaB and C/EBPs in IkappaB-zeta-mediated transcriptional activation.
RL Biochem. J. 405:605-615 (2007).
RN [5]; RE0070219.
RX PUBMED: 19595668.
RA Wu Z., Zhang X., Yang J., Wu G., Zhang Y., Yuan Y., Jin C., Chang Z., Wang J., Yang X., He F.
RT Nuclear protein IkappaB-zeta inhibits the activity of STAT3.
RL Biochem. Biophys. Res. Commun. 387:348-352 (2009).
XX
//