AC T25615
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ID T25615
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DT 15.05.2002 (created); spi.
DT 04.02.2014 (updated); prb.
CO Copyright (C), QIAGEN.
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FA NICD1
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SY NIC-1; Notch 1 intracellular domain.
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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FF high levels of NICD are found in the nuclei of cortical neurons and certain cancers [1];
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IN T08597 alpha-enolase-isoform2; human, Homo sapiens.
IN T24854 alpha-enolase; human, Homo sapiens.
IN T00930 LEF-1; mouse, Mus musculus.
IN T01616 RBPJK; human, Homo sapiens.
IN T08660 YY1; human, Homo sapiens.
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DR TRANSPATH: MO000031225.
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RN [1]; RE0021244.
RX PUBMED: 11604490.
RA Ross D. A., Kadesch T.
RT The notch intracellular domain can function as a coactivator for LEF-1
RL Mol. Cell. Biol. 21:7537-7544 (2001).
RN [2]; RE0062604.
RX PUBMED: 18490439.
RA Hsu K. W., Hsieh R. H., Lee Y. H., Chao C. H., Wu K. J., Tseng M. J., Yeh T. S.
RT The activated Notch1 receptor cooperates with alpha-enolase and MBP-1 in modulating c-myc activity.
RL Mol. Cell. Biol. 28:4829-4842 (2008).
RN [3]; RE0021239.
RX PUBMED: 11331310.
RA Rappold I., Iwabuchi K., Date T., Chen J.
RT Tumor suppressor p53 binding protein 1 (53BP1) is involved in DNA damage-signaling pathways
RL J. Cell Biol. 153:613-620 (2001).
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