TRANSFAC FACTOR TABLE, Release 2017.2 - public - 2017-06-30, (C) QIAGEN

AC T25615 XX ID T25615 XX DT 15.05.2002 (created); spi. DT 04.02.2014 (updated); prb. CO Copyright (C), QIAGEN. XX FA NICD1 XX SY NIC-1; Notch 1 intracellular domain. XX OS human, Homo sapiens OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates XX FF high levels of NICD are found in the nuclei of cortical neurons and certain cancers [1]; XX IN T08597 alpha-enolase-isoform2; human, Homo sapiens. IN T24854 alpha-enolase; human, Homo sapiens. IN T00930 LEF-1; mouse, Mus musculus. IN T01616 RBPJK; human, Homo sapiens. IN T08660 YY1; human, Homo sapiens. XX DR TRANSPATH: MO000031225. XX RN [1]; RE0021244. RX PUBMED: 11604490. RA Ross D. A., Kadesch T. RT The notch intracellular domain can function as a coactivator for LEF-1 RL Mol. Cell. Biol. 21:7537-7544 (2001). RN [2]; RE0062604. RX PUBMED: 18490439. RA Hsu K. W., Hsieh R. H., Lee Y. H., Chao C. H., Wu K. J., Tseng M. J., Yeh T. S. RT The activated Notch1 receptor cooperates with alpha-enolase and MBP-1 in modulating c-myc activity. RL Mol. Cell. Biol. 28:4829-4842 (2008). RN [3]; RE0021239. RX PUBMED: 11331310. RA Rappold I., Iwabuchi K., Date T., Chen J. RT Tumor suppressor p53 binding protein 1 (53BP1) is involved in DNA damage-signaling pathways RL J. Cell Biol. 153:613-620 (2001). XX //