AC T00032
AS T14162, T14945.
XX
ID T00032
XX
DT 15.10.1992 (created); ewi.
DT 07.08.2015 (updated); jmh.
CO Copyright (C), QIAGEN.
XX
FA AP-1
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SY (Jun)2; Activating Protein 1; AP1; Fos/Jun; PEA1; PEA1 (mouse).
XX
OS mouse, Mus musculus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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CL C0008; bZIP.
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SF composed of two subunits: two Jun-peptides or one Jun- T00131 and one Fos-peptide T00122 (or relatives);
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FF AP-1 contributes to the Signal transduction pathway involved in disease resistance [11];
FF DNA binding activity of AP-1 is induced by ERK [11];
FF AP-1 level decreases in murine mammary epithelial cells upon differentiation induced by dexamethasone or prolactin [9];
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IN T00111 c-Ets-1; mouse, Mus musculus.
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MX M00172 V$AP1FJ_Q2.
MX M00517 V$AP1_01.
MX M00199 V$AP1_C.
MX M00173 V$AP1_Q2.
MX M00924 V$AP1_Q2_01.
MX M00188 V$AP1_Q4.
MX M00926 V$AP1_Q4_01.
MX M00174 V$AP1_Q6.
MX M00925 V$AP1_Q6_01.
MX M03538 V$AP1_Q6_02.
XX
BS R02120.
BS R03540.
BS R20747.
BS R20934.
BS R22731.
BS R22753.
BS R24479.
BS R24899.
BS R25252.
BS R25003.
BS R04116.
BS R03445.
BS R62499.
BS R05089.
BS R23069.
BS R23071.
BS R20982.
BS R00468.
BS R31025.
BS R39742.
BS R02887.
BS R74084.
BS R00934.
BS R25018.
BS R73991.
BS R25807.
BS R09882.
BS R30492.
BS R01037.
BS R37765.
BS R68607.
BS R01249.
BS R37740.
BS R25250.
BS R31592.
BS R01564.
BS R02674.
BS R02676.
BS R73999.
BS R14971.
BS R38770.
BS R32138.
BS R61966.
BS R08192.
BS R00133.
BS R55785.
BS R55787.
BS R18416.
BS R37586.
BS R13583.
BS R14970.
BS R37089.
BS R15125.
BS R01050.
BS R30131.
BS R41909.
BS R14620.
BS R14603.
BS R36176.
BS R33368.
BS R74056.
BS R14477.
BS R02348.
BS R02349.
BS R02952.
BS R02953.
BS R05036.
BS R05050.
BS R05052.
BS R26660.
BS R05079.
BS R05098.
BS R23525.
BS R28691.
BS R56283.
BS R60546.
BS R37213.
BS R35955.
BS R01052.
BS R01062.
BS R69126.
BS R16700.
BS R17198.
BS R14160.
BS R34220.
BS R01736.
BS R08476.
BS R61593.
BS R61594.
BS R01286.
BS R01287.
BS R35526.
BS R35528.
BS R35529.
BS R02340.
BS R56073.
BS R31307.
BS R28246.
BS R13173.
BS R13176.
BS R39865.
BS R03300.
BS R20827.
BS R20828.
BS R20830.
BS R28027.
BS R14663.
BS R27905.
BS R33559.
BS R64219.
BS R16979.
BS R01220.
BS R01225.
BS R08470.
BS R08472.
BS R08473.
BS R69064.
XX
DR TRANSPATH: MO000024658.
DR TRANSCOMPEL: C00086.
DR TRANSCOMPEL: C00105.
DR TRANSCOMPEL: C00149.
DR TRANSCOMPEL: C00150.
DR TRANSCOMPEL: C00151.
DR TRANSCOMPEL: C00157.
DR TRANSCOMPEL: C00159.
DR TRANSCOMPEL: C00161.
DR TRANSCOMPEL: C00237.
DR TRANSCOMPEL: C00238.
DR TRANSCOMPEL: C00251.
DR TRANSCOMPEL: C00264.
DR TRANSCOMPEL: C00316.
DR TRANSCOMPEL: C00354.
DR TRANSCOMPEL: C00604.
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RN [1]; RE0000394.
RX PUBMED: 3038517.
RA Piette J., Yaniv M.
RT Two different factors bind to the alpha-domain of the polyoma virus enhancer, one of which also interacts with the SV40 and c-fos enhancers
RL EMBO J. 6:1331-1337 (1987).
RN [2]; RE0001018.
RX PUBMED: 1849903.
RA Campbell C. E., Flenniken A. M., Skup D., Williams B. R. G.
RT Identification of a serum- and phorbol ester-responsive element in the murine tissue inhibitor of metalloproteinase gene
RL J. Biol. Chem. 266:7199-7206 (1991).
RN [3]; RE0001819.
RX PUBMED: 3037385.
RA Kryszke M.-H., Piette J., Yaniv M.
RT Induction of a factor that binds to the polyoma virus A enhancer on differentiation of embryonal carcinoma cells
RL Nature 328:254-256 (1987).
RN [4]; RE0002008.
RX PUBMED: 2922288.
RA Rittling S. R., Coutinho L., Amram T., Kolbe M.
RT Ap-1/jun binding sites mediate serum inducibility of the human vimentin promoter
RL Nucleic Acids Res. 17:1619 (1989).
RN [5]; RE0002020.
RX PUBMED: 2911469.
RA Mignotte V., Wall L., deBoer E., Grosveld F., Romeo P.-H.
RT Two tissue-specific factors bind to the erythroid promoter of the human porphobilinogen deaminase gene
RL Nucleic Acids Res. 17:37-54 (1989).
RN [6]; RE0002339.
RX PUBMED: 2842750.
RA Martin M. E., Piette J., Yaniv M., Tang W.-J., Folk W. R.
RT Activator of the polyomavirus enhancer by a murine activator protein 1 (AP1) homolog and two contiguous proteins
RL Proc. Natl. Acad. Sci. USA 85:5839-5843 (1988).
RN [7]; RE0002408.
RX PUBMED: 2453058.
RA Piette J., Hirai S.-I., Yaniv M.
RT Constitutive synthesis of activator protein 1 transcription factor after viral transformation of mouse fibroblasts
RL Proc. Natl. Acad. Sci. USA 85:3401-3405 (1988).
RN [8]; RE0002621.
RX PUBMED: 3125612.
RA Korber B., Mermod N., Hood L., Stroynowski I.
RT Regulation of Gene Expression by Interferons: Control of H-2 Promoter Responses
RL Science 239:1302-1306 (1988).
RN [9]; RE0003004.
RX PUBMED: 1508191.
RA Jehn B., Costello E., Marti A., Keon N., Deane R., Li F., Friis R. R., Burri P. H., Martin F., Jaggi R.
RT Overexpression of Mos, Ras, Src, and Fos inhibits mouse mammary epithelial cell differentiation
RL Mol. Cell. Biol. 12:3890- 3902 (1992).
RN [10]; RE0013315.
RX PUBMED: 8557686.
RA Logan S. K., Garabedian M. J., Campbell C. E., Werb Z.
RT Synergistic transcriptional activation of the tissue inhibitor of metalloproteinases-1 promoter via functional interaction of AP-1 and Ets-1 transcription factors
RL J. Biol. Chem. 271:774-782 (1996).
RN [11]; RE0053111.
RX PUBMED: 12438359.
RA Ghosh S., Bhattacharyya S., Sirkar M., Sa G. S., Das T., Majumdar D., Roy S., Majumdar S.
RT Leishmania donovani suppresses activated protein 1 and NF-kappaB activation in host macrophages via ceramide generation: involvement of extracellular signal-regulated kinase.
RL Infect. Immun. 70:6828-6838 (2002).
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