AC T00052
XX
ID T00052
XX
DT 15.10.1992 (created); ewi.
DT 17.10.2012 (updated); mkl.
CO Copyright (C), QIAGEN.
XX
FA ATFa-isoform6
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SY Activating Transcription Factor a; ATF-a; ATF-a2.
XX
OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G004956 ATF7; HGNC: ATF7.
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CL C0008; bZIP.
XX
SZ 483 AA; 51.8 kDa (cDNA) (calc.).
XX
SQ MGDDRPFVCNAPGCGQRFTNEDHLAVHKHKHEMTLKFGPARTDSVIIADQTPTPTRFLKN
SQ CEEVGLFNELASSFEHEFKKAADEDEKKAAAGPLDMSLPSTPDIKIKEEEPVEVDSSPPD
SQ SPASSPCSPPLKEKEVTPKPVLISTPTPTIVRPGSLPLHLGYDPLHPTLPSPTSVITQAP
SQ PSNRQMGSPTGSLPLVMHLANGQTMPVLPGPPVQMPSVISLARPVSMVPNIPGIPGPPVN
SQ SSGSISPSGHPIPSEAKMRLKATLTHQVSSINGGCGMVVGTASTMVTARPEQSQILIQHP
SQ DAPSPAQPQVSPAQPTPSTGGRRRRTVDEDPDERRQRFLERNRAAASRCRQKRKLWVSSL
SQ EKKAEELTSQNIQLSNEVTLLRNEVAQLKQLLLAHKDCPVTALQKKTQGYLESPKESSEP
SQ TGSPAPVIQHSSATAPSNGLSVRSAAEAVATSVLTQMASQRTELSMPIQSHVIMTPQSQS
SQ AGR
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SC Swiss-Prot#P17544-6
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FT 7 31 
PF00096; zf-C2H2.
FT 7 31 
PS50157; ZINC_FINGER_C2H2_2.
FT 7 31 
SM00355; c2h2final6.
FT 158 477 
PF00478; IMP dehydrogenase / GMP reductase domain.
FT 330 394 
PF00170; bZIP transcription factor.
FT 330 394 
SM00338; brlzneu.
FT 332 395 
PS50217; BZIP.
XX
SF interacting with both NF-kappaB subunits [2];
SF with NF-kappaB, ATFa-isoform6 forms the NF-ELAM1 complex found to bind to the E-selectin promoter [2];
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CP (HeLa).
XX
IN T00593 NF-kappaB1-p50; human, Homo sapiens.
IN T00594 RelA-p65-isoform1; human, Homo sapiens.
IN T00915 YY1; human, Homo sapiens.
XX
MX M00981 V$CREBATF_Q6.
MX M00801 V$CREB_Q3.
XX
BS R00322.
BS R02126.
BS R11552.
BS R72580.
XX
DR TRANSPATH: MO000020842.
DR TRANSCOMPEL: C00093.
DR TRANSCOMPEL: C00097.
DR TRANSCOMPEL: C00102.
DR TRANSCOMPEL: C00103.
DR TRANSCOMPEL: C00634.
DR EMBL: X52943; HSATFA.
DR UniProtKB: P17544-6; ATF7_HUMAN.
XX
RN [1]; RE0002771.
RX PUBMED: 1694576.
RA Gaire M., Chatton B., Kedinger C.
RT Isolation and characterization of two novel, closely related ATF cDNA clones from HeLa cells
RL Nucleic Acids Res. 18:3467-3473 (1990).
RN [2]; RE0004521.
RX PUBMED: 7692236.
RA Kaszubska W., Hooft van Huijsduijnen R., Ghersa P., DeRaemy-Schenk A.-M., Chen B. P. C., Hai T., DeLamarter J. F., Whelan J.
RT Cyclic AMP-independent ATF family members interact with NF-kappaB and function in the activation of the E-selectin promoter in response to cytokines
RL Mol. Cell. Biol. 13:7180-7190 (1993).
RN [3]; RE0047834.
RX PUBMED: 7769693.
RA Zhou Q., Gedrich R. W., Engel D. A.
RT Transcriptional repression of the c-fos gene by YY1 is mediated by a direct interaction with ATF/CREB.
RL J. Virol. 69:4323-4330 (1995).
XX
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