AC T00178
XX
ID T00178
XX
DT 15.10.1992 (created); ewi.
DT 31.05.2005 (updated); oke.
CO Copyright (C), QIAGEN.
XX
FA CTF-3
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SY CTF-3; ctf/nf-1; NFI; NFI/CTF-3; NFIC isoform 3; NFIC3.
XX
OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G003997 NFIC; HGNC: NFIC.
XX
CL C0060; NF1; 7.1.2.0.3.3.
XX
SZ 406 AA; 45.4 kDa (cDNA) (calc.).
XX
SQ MDEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKDEERAVKDELLGEKPEVK
SQ QKWASRLLAKLRKDIRPECREDFVLSITGKKAPGCVLSNPDQKGKMRRIDCLRQADKVWR
SQ LDLVMVILFKGIPLESTDGERLVKAAQCGHPVLCVQPHHIGVAVKELDLYLAYFVRERDT
SQ TDFQESFVTSGVFSVTELIQVSRTPVVTGTGPNFSLGELQGHLAYDLNPASTGLRRTLPS
SQ TSSSGSKRHKSGSMEEDVDTSPGGDYYTSPSSPTSSSRNWTEDMEGGISSPVKKTEMDKS
SQ PFNSPSPQDSPRLSSFTQHHRPVIAVHSGIARSPHPSSALHFPTTSILPQTASTYFPHTA
SQ IRYPPHLNPQDPLKDLVSLACDPASQQPGPPTLRPTRPLQTVPLWD
XX
SC Swiss-Prot#P08651-4
XX
FT 1 186 
PS51080; CTF_NFI_2.
FT 16 335 
PF00478; IMP dehydrogenase / GMP reductase domain.
FT 57 164 
PF03165; MH1 domain.
FT 59 167 
SM00523; dwAneu5.
FT 184 406 
PF00859; CTF/NF-I family transcription modulation reg.
XX
SF 6 splice variants are known: NF-1 T00539, CTF-1 T00176, CTF-2 T00177, CTF-3 (this entry), CTF-5 T02300, CTF-7 T02301 [3] [4];
XX
MX M01196 V$CTF1_01.
MX M00056 V$MYOGNF1_01.
MX M07300 V$NF1C_Q6.
MX M07363 V$NF1FAMILY_Q4.
MX M00193 V$NF1_Q6.
MX M00806 V$NF1_Q6_01.
MX M07364 V$NF1_Q6_02.
XX
BS R00506.
BS R01311.
XX
DR TRANSPATH: MO000009776.
DR EMBL: X12492; HSCTF1.
DR UniProtKB: P08651-4;
XX
RN [1]; RE0000148.
RX PUBMED: 2504497.
RA Mermod N., O'Neill E. A., Kelly T. J., Tjian R.
RT The Proline-Rich Transcriptional Activator of CTF/NF-I Is Distinct from the Replication and DNA Binding Domain
RL Cell 58:741-753 (1989).
RN [2]; RE0001784.
RX PUBMED: 3398920.
RA Santoro C., Mermod N., Andrews P. C., Tjian R.
RT A family of human CCAAT-box-binding proteins active in transcription and DNA replication: cloning and expression of multiple cDNAs
RL Nature 334:218-224 (1988).
RN [3]; RE0003054.
RX PUBMED: 8171010.
RA Altmann H., Wendler W., Winnacker E. L.
RT Transcriptional activation by CTF proteins is mediated by a bipartite low-proline domain
RL Proc. Natl. Acad. Sci. USA 91:3901-3905 (1994).
RN [4]; RE0006390.
RX PUBMED: 8710515.
RA Wenzelides S., Altmann H., Wendler W., Winnacker E.-L.
RT CTF5- a new transcriptional activator of the NFI/CTF family
RL Nucleic Acids Res. 24:2416-2421 (1996).
XX
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