AC T01003
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ID T01003
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DT 25.01.1994 (created); ewi.
DT 13.03.2013 (updated); spk.
CO Copyright (C), QIAGEN.
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FA SSRP1
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SY CIIDBP; SSRP1; structure-specific recognition protein 1; T160 (mouse); VDJ-recombination signal binding protein.
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G004675 SSRP1; HGNC: SSRP1.
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HO Ixr1 (yeast).
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CL C0015; HMG; 4.1.5.0.2.
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SF binds to distorted DNA structures [1];
SF murine homolog: VDJ-recombination signal binding protein;
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FF co-activator for SRF;
FF co-activator for p63gamma, associate directly with the DNA-bound p63gamma [4];
FF enhances p63gamma-induced G1 arrest and apoptosis [4];
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IN T00140 c-Myc-isoform1; human, Homo sapiens.
IN T06243 HMGB1; human, Homo sapiens.
IN T06135 p63-isoform5; human, Homo sapiens.
IN T04931 p73alpha; human, Homo sapiens.
IN T34680 PD2; human, Homo sapiens.
IN T10037 PU.1; Mammalia.
IN T19717 RHA; human, Homo sapiens.
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DR TRANSPATH: MO000025334.
DR UniProtKB: Q08945;
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RN [1]; RE0002537.
RX PUBMED: 1372440.
RA Bruhn S. L., Pil P. M., Essigmann J. M., Housman D. E., Lippard S. J.
RT Isolation and characterization of human cDNA clones encoding a high mobility group box protein that recognizes structural distortions to DNA caused by binding of the anticancer agent cisplatin
RL Proc. Natl. Acad. Sci. USA 89:2307-2311 (1992).
RN [2]; RE0004344.
RX PUBMED: 2530581.
RA Toney J. H., Donahue B. A., Kellett P. J., Bruhn S. L., Essigmann J. M., Lippard S. J.
RT Isolation of cDNAs encoding a human protein that binds selectively to DNA modified by the anticancer drug cis-diammine-dichloroplatinum (II)
RL Proc. Natl. Acad. Sci. USA 86:8328-8332 (1989).
RN [3]; RE0004371.
RX PUBMED: 7862532.
RA Bunker C. A., Kingston R. E.
RT Identification of a cDNA for SSRP1, an HMG-box protein, by interaction with the c-Myc oncoprotein in a novel bacterial expression screen
RL Nucleic Acids Res. 23:269-276 (1995).
RN [4]; RE0024348.
RX PUBMED: 12374749.
RA Zeng S. X., Dai M. S., Keller D. M., Lu H.
RT SSRP1 functions as a co-activator of the transcriptional activator p63.
RL EMBO J. 21:5487-5497 (2002).
RN [5]; RE0047237.
RX PUBMED: 7594592.
RA Nagulapalli S., Pongubala J. M., Atchison M. L.
RT Multiple proteins physically interact with PU.1. Transcriptional synergy with NF-IL6 beta (C/EBP delta, CRP3)
RL J. Immunol. 155:4330-8 (1995).
RN [6]; RE0048218.
RX PUBMED: 16226712.
RA Niture S. K., Doneanu C. E., Velu C. S., Bailey N. I., Srivenugopal K. S.
RT Proteomic analysis of human O6-methylguanine-DNA methyltransferase by affinity chromatography and tandem mass spectrometry.
RL Biochem. Biophys. Res. Commun. 337:1176-1184 (2005).
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