TRANSFAC FACTOR TABLE, Release 2017.2 - public - 2017-06-30, (C) QIAGEN

AC T01003 XX ID T01003 XX DT 25.01.1994 (created); ewi. DT 13.03.2013 (updated); spk. CO Copyright (C), QIAGEN. XX FA SSRP1 XX SY CIIDBP; SSRP1; structure-specific recognition protein 1; T160 (mouse); VDJ-recombination signal binding protein. XX OS human, Homo sapiens OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates XX GE G004675 SSRP1; HGNC: SSRP1. XX HO Ixr1 (yeast). XX CL C0015; HMG; XX SF binds to distorted DNA structures [1]; SF murine homolog: VDJ-recombination signal binding protein; XX FF co-activator for SRF; FF co-activator for p63gamma, associate directly with the DNA-bound p63gamma [4]; FF enhances p63gamma-induced G1 arrest and apoptosis [4]; XX IN T00140 c-Myc-isoform1; human, Homo sapiens. IN T06243 HMGB1; human, Homo sapiens. IN T06135 p63-isoform5; human, Homo sapiens. IN T04931 p73alpha; human, Homo sapiens. IN T34680 PD2; human, Homo sapiens. IN T10037 PU.1; Mammalia. IN T19717 RHA; human, Homo sapiens. XX DR TRANSPATH: MO000025334. DR UniProtKB: Q08945; XX RN [1]; RE0002537. RX PUBMED: 1372440. RA Bruhn S. L., Pil P. M., Essigmann J. M., Housman D. E., Lippard S. J. RT Isolation and characterization of human cDNA clones encoding a high mobility group box protein that recognizes structural distortions to DNA caused by binding of the anticancer agent cisplatin RL Proc. Natl. Acad. Sci. USA 89:2307-2311 (1992). RN [2]; RE0004344. RX PUBMED: 2530581. RA Toney J. H., Donahue B. A., Kellett P. J., Bruhn S. L., Essigmann J. M., Lippard S. J. RT Isolation of cDNAs encoding a human protein that binds selectively to DNA modified by the anticancer drug cis-diammine-dichloroplatinum (II) RL Proc. Natl. Acad. Sci. USA 86:8328-8332 (1989). RN [3]; RE0004371. RX PUBMED: 7862532. RA Bunker C. A., Kingston R. E. RT Identification of a cDNA for SSRP1, an HMG-box protein, by interaction with the c-Myc oncoprotein in a novel bacterial expression screen RL Nucleic Acids Res. 23:269-276 (1995). RN [4]; RE0024348. RX PUBMED: 12374749. RA Zeng S. X., Dai M. S., Keller D. M., Lu H. RT SSRP1 functions as a co-activator of the transcriptional activator p63. RL EMBO J. 21:5487-5497 (2002). RN [5]; RE0047237. RX PUBMED: 7594592. RA Nagulapalli S., Pongubala J. M., Atchison M. L. RT Multiple proteins physically interact with PU.1. Transcriptional synergy with NF-IL6 beta (C/EBP delta, CRP3) RL J. Immunol. 155:4330-8 (1995). RN [6]; RE0048218. RX PUBMED: 16226712. RA Niture S. K., Doneanu C. E., Velu C. S., Bailey N. I., Srivenugopal K. S. RT Proteomic analysis of human O6-methylguanine-DNA methyltransferase by affinity chromatography and tandem mass spectrometry. RL Biochem. Biophys. Res. Commun. 337:1176-1184 (2005). XX //