AC T01082
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ID T01082
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DT 24.02.1994 (created); ewi.
DT 12.06.2009 (updated); smt.
CO Copyright (C), QIAGEN.
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FA NRL
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SY AS321; D14S46E; neural retina-specific leucine zipper protein.
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G003947 NRL; HGNC: NRL.
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CL C0008; bZIP; 1.1.3.1.4.
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SF belongs to the Maf-family because of an extended region of homology N-terminally to the basic region [1];
SF cross-hybridizing genes in many vertebrates, Drosophila, yeast indicate high degree of conservation during evolution [1];
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CP retina [1].
CN brain, kidney, liver, lung, muscle, retinal pigment epithelial cells, thymus [1].
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IN T00123 c-Fos; human, Homo sapiens.
IN T00133 c-Jun; human, Homo sapiens.
IN T01430 v-Maf; AS42, avian musculoaponeurotic fibrosarcoma virus.
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MX M04224 V$NRL_01.
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BS R28133.
BS R15741.
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DR TRANSPATH: MO000010120.
DR PATHODB: MT010505.
DR UniProtKB: P54845;
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RN [1]; RE0002541.
RX PUBMED: 1729696.
RA Swaroop A., Xu J., Pawar H., Jackson A., Skolnick C., Agarwal N.
RT A conserved retina-specific gene encodes a basic motif/leucine zipper domain
RL Proc. Natl. Acad. Sci. USA 89:266-270 (1992).
RN [2]; RE0004866.
RX PUBMED: 8108109.
RA Kerppola T. K., Curran T.
RT Maf and Nrl can bind to AP-1 sites and form heterodimers with Fos and Jun
RL Oncogene 9:675-684 (1994).
RN [3]; RE0012903.
RX PUBMED: 8552602.
RA Rehemetulla A., Warwar R., Kumar R., Ji X., Zack D. J., Swaroop A.
RT The basic motif-leucine zipper transcription factor Nrl can positively regulate rhodopsin gene expression
RL Proc. Natl. Acad. Sci. USA 93:191-195 (1996).
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