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TRANSFAC FACTOR TABLE, Release 2017.2 - public - 2017-06-30, (C) QIAGEN


AC T01316 XX ID T01316 XX DT 23.10.1994 (created); ewi. DT 16.07.2012 (updated); mkl. CO Copyright (C), QIAGEN. XX FA CREMgamma XX SY CREMgamma. XX OS mouse, Mus musculus OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae XX GE G000532 Crem. XX CL C0008; bZIP; 1.1.7.1.3.4. XX SZ 233 AA; 26.1 kDa (cDNA) (calc.). XX SQ MSKCGRKKYMRTNVRQMTMETVESQQDRSVTRSVAEHSSAHMQTGQISVPTLAQVATIAE SQ TDDSADSEVIDSHKRREILSRRPSYRKILNELSSDVPGIPKIEEEKSEEEGTPPNIATMA SQ VPTSIYQTSTGQYTATGDMPTYQIRAPTTALPQGVVMAASPGSLHSPQQLAEEATRKREL SQ RLMKNREAAKECRRRKKEYVKCLESRVAVLEVQNKKLIEELETLKDICSPKTD XX SC Swiss-Prot#P27699-4 XX FT 36 95 PS50953; KID. FT 48 88 PF02173; pKID domain. FT 157 214 SM00338; brlzneu. FT 157 217 PF00170; bZIP transcription factor. FT 159 210 PS50217; BZIP. XX SF encoded by exons 1 (B), 3 (E), 4 (F), 7 (H), and the 3'-half of exon 8 (Ib) [5]; SF several alternative splice variants [1]; XX CP mRNA: pituitary gland, brain, kidney, heart [2]. CN not found in testis [2]. XX FF repressor, CREB antagonist as dominant negative regulator [1] [4]; XX IN T00989 CREB; mouse, Mus musculus. IN T01316 CREMgamma; mouse, Mus musculus. IN T01309 CREMtau; mouse, Mus musculus. IN T01319 ICER; rat, Rattus norvegicus. XX MX M00981 V$CREBATF_Q6. MX M00916 V$CREB_Q2_01. MX M00801 V$CREB_Q3. MX M00917 V$CREB_Q4_01. MX M01820 V$CREM_Q6. MX M08803 V$CREM_Q6_01. XX BS R01358. XX DR TRANSPATH: MO000025576. DR EMBL: M60285; DR UniProtKB: P27699-4; XX RN [1]; RE0000262. RX PUBMED: 1847666. RA Foulkes N. S., Borrelli E., Sassone-Corsi P. RT CREM gene: use of alternative DNA-binding domains generates multiple antagonists of cAMP-induced transcription RL Cell 64:739-749 (1991). RN [2]; RE0001912. RX PUBMED: 1370576. RA Foulkes N. S., Mellstroem B., Benusiglio E., Sassone-Corsi P. RT Developmental switch of CREM function during spermatogenesis: from antagonist to activator RL Nature 355:80-84 (1992). RN [3]; RE0001915. RX PUBMED: 8397338. RA Stehle J. H., Foulkes N. S., Molina C. A., Simonneaux V., Pevet P., Sassone-Corsi P. RT Adrenergic signals direct rhythmic expression of transcriptional repressor CREM in the pineal gland RL Nature 365:314-320 (1993). RN [4]; RE0003158. RX PUBMED: 8458330. RA Laoide B.M., Foulkes N.S., Schlotter F., Sassone-Corsi P. RT The functional versatility of CREM is determined by its modular structure RL EMBO J. 12:1179-1191 (1993). RN [5]; RE0000035. RX PUBMED: 6537904. RA Parker C. S., Topol J. RT A Drosophila RNA polymerase II transcription factor contains a promoter-region-specific DNA-binding activity RL Cell 36:357-369 (1984). XX //