AC T01316
XX
ID T01316
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DT 23.10.1994 (created); ewi.
DT 16.07.2012 (updated); mkl.
CO Copyright (C), QIAGEN.
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FA CREMgamma
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SY CREMgamma.
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OS mouse, Mus musculus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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GE G000532 Crem.
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CL C0008; bZIP; 1.1.7.1.3.4.
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SZ 233 AA; 26.1 kDa (cDNA) (calc.).
XX
SQ MSKCGRKKYMRTNVRQMTMETVESQQDRSVTRSVAEHSSAHMQTGQISVPTLAQVATIAE
SQ TDDSADSEVIDSHKRREILSRRPSYRKILNELSSDVPGIPKIEEEKSEEEGTPPNIATMA
SQ VPTSIYQTSTGQYTATGDMPTYQIRAPTTALPQGVVMAASPGSLHSPQQLAEEATRKREL
SQ RLMKNREAAKECRRRKKEYVKCLESRVAVLEVQNKKLIEELETLKDICSPKTD
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SC Swiss-Prot#P27699-4
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FT 36 95 PS50953; KID.
FT 48 88 PF02173; pKID domain.
FT 157 214 SM00338; brlzneu.
FT 157 217 PF00170; bZIP transcription factor.
FT 159 210 PS50217; BZIP.
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SF encoded by exons 1 (B), 3 (E), 4 (F), 7 (H), and the 3'-half of exon 8 (Ib) [5];
SF several alternative splice variants [1];
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CP mRNA: pituitary gland, brain, kidney, heart [2].
CN not found in testis [2].
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FF repressor, CREB antagonist as dominant negative regulator [1] [4];
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IN T00989 CREB; mouse, Mus musculus.
IN T01316 CREMgamma; mouse, Mus musculus.
IN T01309 CREMtau; mouse, Mus musculus.
IN T01319 ICER; rat, Rattus norvegicus.
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MX M00981 V$CREBATF_Q6.
MX M00916 V$CREB_Q2_01.
MX M00801 V$CREB_Q3.
MX M00917 V$CREB_Q4_01.
MX M01820 V$CREM_Q6.
MX M08803 V$CREM_Q6_01.
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BS R01358.
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DR TRANSPATH: MO000025576.
DR EMBL: M60285;
DR UniProtKB: P27699-4;
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RN [1]; RE0000262.
RX PUBMED: 1847666.
RA Foulkes N. S., Borrelli E., Sassone-Corsi P.
RT CREM gene: use of alternative DNA-binding domains generates multiple antagonists of cAMP-induced transcription
RL Cell 64:739-749 (1991).
RN [2]; RE0001912.
RX PUBMED: 1370576.
RA Foulkes N. S., Mellstroem B., Benusiglio E., Sassone-Corsi P.
RT Developmental switch of CREM function during spermatogenesis: from antagonist to activator
RL Nature 355:80-84 (1992).
RN [3]; RE0001915.
RX PUBMED: 8397338.
RA Stehle J. H., Foulkes N. S., Molina C. A., Simonneaux V., Pevet P., Sassone-Corsi P.
RT Adrenergic signals direct rhythmic expression of transcriptional repressor CREM in the pineal gland
RL Nature 365:314-320 (1993).
RN [4]; RE0003158.
RX PUBMED: 8458330.
RA Laoide B.M., Foulkes N.S., Schlotter F., Sassone-Corsi P.
RT The functional versatility of CREM is determined by its modular structure
RL EMBO J. 12:1179-1191 (1993).
RN [5]; RE0000035.
RX PUBMED: 6537904.
RA Parker C. S., Topol J.
RT A Drosophila RNA polymerase II transcription factor contains a promoter-region-specific DNA-binding activity
RL Cell 36:357-369 (1984).
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